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抗体

磷酸化PNK(Ser114, Thr118)多克隆抗体

PA5-17013

100µL

375.00美元

多克隆

domestic rabbit

未共轭

磷酸化

磷酸化PNK(Ser114, Thr118)多克隆抗体

PA5-17013

100µL

375.00美元

多克隆

抗原亲和色谱

兔

人类

Western Blot: 1:1000

人类

IgG

-20°C

Anti-human Polynucleotide Kinase Mouse Monoclonal Antibody recognizes polynucleotide kinase (PNK), a 57 kDa nuclear enzyme implicated in DNA strand repair processes that occur during DNA replication and recombination, or in response to DNA damaging agents. PNK targets the DNA 5'-hydroxy and 3'-phosphate termini for phosphorylation and dephosphorylation events. During strand breakage in human cells, normal PNK associates with other nuclear proteins to prepare the DNA termini for the enzymatic actions of DNA polymerase-beta and DNA ligase III. PNK is a key functional component in maintaining the genetic stability of human cells.

Synthetic phosphopeptide corresponding to residues around pSer114 and pThr118 of human PNK1

液体

Western Blot: 1:1000

1810009G08Rik; 2'(3')-polynucleotidase; AOA4; Bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase; EIEE10; Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP); MCSZ; phosphatase/kinase; PKNP; PNK; PNKP; Polynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase; polynucleotide kinase 3'- phosphatase; polynucleotide kinase 3'-phosphatase; Polynucleotide kinase-3'-phosphatase