产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ATG3多克隆抗体
目录 :
PA5-17018
规格 :
100微升
价格 :
美国325.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, 犬, 鸡, 牛, 非洲爪蛙
应用 :
免疫印迹
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
ATG3多克隆抗体
目录# :
PA5-17018
规格 :
100微升
价格 :
美国325.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
Bovine, Canine, Chicken, Human, Mouse, Non-human primate, Rat, Xenopus laevis
应用 :
Western Blot: 1:1,000
物种 :
Bovine, Canine, Chicken, Human, Mouse, Non-human primate, Rat, Xenopus laevis
抗体亚型 :
IgG
储存 :
-20°C
描述 :
ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. Autophagy is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG3 functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy.
免疫原 :
Synthetic peptide corresponding to residues near the amino terminus of Atg3
格式 :
液体
应用w/稀释 :
Western Blot: 1:1,000
别名 :
2610016C12Rik; APG3; Apg3l; APG3-like; Apg3p; atg3; ATG3 autophagy related 3 homolog; atg3.S; Atg3l; autophagy related 3; autophagy related 3 S homeolog; autophagy-related 3; autophagy-related protein 3; DKFZp564M1178; EGK_11288; FLJ22125; hApg3; MGC15201; PC3-96; Pig1; PIG-1; preconditioning-inducible gene 1 protein; Protein PC3-96; Ubiquitin-like-conjugating enzyme ATG3; XELAEV_18014721mg
更多信息或购买 :
公司信息
赛默飞世尔