产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TIRAP多克隆抗体
目录 :
PA5-17970
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
图像
图像 1 :
赛默飞世尔 PA5-17970 图像 1
Western Blot staining of Human Liver lysate using PA5-17970 at a concentration of 1.0 ug/ml, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.
产品信息
产品类型 :
抗体
产品名称 :
TIRAP多克隆抗体
目录# :
PA5-17970
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
纯度 :
硫酸铵沉淀
宿主 :
山羊
反应物种 :
人类
应用 :
Western Blot: 1-3 µg/mL
物种 :
人类
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as TIRAP and MyD88 to activate various kinases and transcription factors. In TIRAP-deficient mice, TLR signaling in response to TLR2 ligands (using either TLR1 and TLR6 as co-receptors) is totally abolished, suggesting that MyD88 and TIRAP work together and are both required for TLR2 signaling. Furthermore, these mice are also resistant to the toxic effects of LPS and show defects in NF- B and MAP kinase activation, suggesting that TIRAP is also involed in TLR4 signaling.
免疫原 :
Synthetic peptide sequence (EGEGERDSATVSDL) corresponding to the C-terminus amino acids of TIRAP
格式 :
液体
应用w/稀释 :
Western Blot: 1-3 µg/mL
别名 :
AA407980; adapter protein wyatt; adaptor protein Wyatt; BACTS1; C130027E04Rik; FLJ42305; HGNC:17192; Mal; myD88 adapter-like protein; MyD88-2; OTTHUMP00000179130; TIR domain containing adaptor protein; TIR domain-containing adapter protein; TIRAP; Tlr4ap; toll/interleukin-1 receptor domain-containing adapter protein; toll-interleukin 1 receptor (TIR) domain containing adaptor protein; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein; Toll-like receptor 4 adaptor protein; Toll-like receptor adaptor protein; Wyatt
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国