产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
OGG1多克隆抗体
目录 :
PA5-18747
规格 :
100微克
价格 :
美国436.00
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
图像
图像 1 :
Western Blot staining of Rat Spleen lysate using PA5-18747 at a concentration of 0.1 ug/ml, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.
产品信息
产品类型 :
抗体
产品名称 :
OGG1多克隆抗体
目录# :
PA5-18747
规格 :
100微克
价格 :
美国436.00
克隆性 :
多克隆
纯度 :
硫酸铵沉淀
宿主 :
山羊
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunohistochemistry: 5 µg/mL, Western Blot: 0.1-0.3 µg/mL
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
8-hydroxyguanine, a form of oxidative DNA damage induced by free radicals, causes G:C to T:A transversion. In E. Coli, three DNA repair enzymes exist to prevent the mutagenic effects of 8-hydroxyguanine. One of these enzymes, MutM, was found to have a functional yeast (yOgg1) and human (hOgg1) homologue. hOgg1 proteins efficiently released the 8-hydroxyguanine opposite the pyrimidine from DNA and cleaved the AP site in a manner similar to bacterial and yeast enzymes. Genetic backgrounds in control of the repair of damaged DNA are involved in the susceptibility to cancer development. The hOgg1 gene has been mapped to region 3p26. 2, a region showing loss of heterozygosity (LOH) in a variety of cancers. In particular, 3p25-p26 is a common LOH region in lung cancer.
免疫原 :
合成肽序列(HPKTSQAKGPSPLANK)对应于。。。的内部氨基酸OGG1
格式 :
液体
应用w/稀释 :
Immunohistochemistry: 5 µg/mL, Western Blot: 0.1-0.3 µg/mL
别名 :
8-hydroxyguanine DNA glycosylase; 8-oxoguanine DNA glycosylase; 8-oxoguanine DNA-glycosylase 1; 8-oxoguanine-DNA-glycosylase; AP lyase; DNA-(apurinic or apyrimidinic site) lyase; DNA-apurinic or apyrimidinic site lyase; HMMH; HOGG1; Mmh; MUTM; N-glycosylase/DNA lyase; OGG1; OGG1 type 1f; OGH1
更多信息或购买 :
公司信息
赛默飞世尔