产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TRPC4多克隆抗体
目录 :
PA5-18987
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
Western Blot staining of Rat Brain lysate using PA5-18987 at a concentration of 0.3 ug/ ml, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.
产品信息
产品类型 :
抗体
产品名称 :
TRPC4多克隆抗体
目录# :
PA5-18987
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
纯度 :
硫酸铵沉淀
宿主 :
山羊
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunohistochemistry (Paraffin): 4.75 µg/mL, Western Blot: 0.3-1 µg/mL
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
TRPC4 is a member of the canonical subfamily of transient receptor potential cation channels. TRPC4 forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in TRPC4 may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TRPC4. The classical or canonical transient receptor potential (TRPC) channels are the subfamily most closely related to the founding member of the TRP family, the Drosophila TRP channel. TRPC channels have seven TRPC genes that encode the channel protein (TRPC1-7). Diseases associated with TRPC4 include Photosensitive Epilepsy.CaV3.3 encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by CaV3.3 is characterized by a slower activation and inactivation compared to other T-type calcium channels. CaV3.3 may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants of CaV3.3. Voltage-gated calcium channels (CaV) are present in the membrane of most excitable cells and mediate calcium influx in response to depolarization, an proteins such as CaV3.3 regulate intracellular processes such as contraction, secretion, neurotransmission and gene expression. Diseases associated with CACNA1I include Childhood Absence Epilepsy.
免疫原 :
合成肽序列(KHAKEEDSSIDYD)对应于。。。的内部氨基酸TRPC4
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 4.75 µg/mL, Western Blot: 0.3-1 µg/mL
别名 :
alpha TRPC4; beta TRPC4; beta-2 TRPC4; capacitative calcium entry channel 1; capacitative calcium entry channel Trp4; CCE1; HTRP4; HTRP-4; MGC119570; MGC119571; MGC119572; MGC119573; putative capacitative calcium entry channel; receptor-activated cation channel TRP4; Short transient receptor potential channel 4; STRPC4; transient receptor potential cation channel subfamily C member 4; transient receptor potential cation channel, subfamily C, member 4; transient receptor potential channel 4; transient receptor potential protein 4; transient receptor protein 4; Trp4; TRPC 4; Trpc4; Trpc4_v2; trp-related protein 4; Trrp4
更多信息或购买 :
公司信息
赛默飞世尔