产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
核不均一核糖核蛋白A1多克隆抗体
目录 :
PA5-19431
规格 :
100微克
价格 :
美国496.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 核糖核酸免疫沉淀
更多信息或购买 :
文章摘录数: 3
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:3000; 图 s1e
Nozawa R, Boteva L, Soares D, Naughton C, Dun A, Buckle A, et al. SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs. Cell. 2017;169:1214-1227.e18 pubmed 出版商
Kooshapur H, Choudhury N, Simon B, Mühlbauer M, Jussupow A, Fernandez N, et al. Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1. Nat Commun. 2018;9:2479 pubmed 出版商
Fernandez N, Cordiner R, Young R, Hug N, Macias S, Caceres J. Genetic variation and RNA structure regulate microRNA biogenesis. Nat Commun. 2017;8:15114 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA5-19431 图像 1
Western blot analysis of HepG2 whole cell lysate using PA5-19431, hnRNP A1 primary antibody at a dilution of 1 ug/ml (lane 1). PA5-19431 staining of MCF7 whole cell lysate at a dilution of 1 ug/ml (Lane 2). PA5-19431 staining of SHSY-5Y whole cell lysate at a dilution of 1 ug/ml (lane 3). Blot treated with a secondary IR Dye680-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:10000.
图像 2 :
赛默飞世尔 PA5-19431 图像 2
Immunohistochemical (formalin-fixed, paraffin-embedded) staining of human skin tissue tissue using PA5-19431, anti-hnRNP A1 antibody. Primary antibody was used at a concentration of 5 ug/ml and exposed for 15 mins at room temp. The sample was pretreated using heat mediated antigen retrieval with Sodium Citrate Buffer (pH6 / 20mins). The detection method was a HRP conjugated polymer, DAB chromogen and the sample was counterstained with haematoxylin and mounted with DPX.
产品信息
产品类型 :
抗体
产品名称 :
核不均一核糖核蛋白A1多克隆抗体
目录# :
PA5-19431
规格 :
100微克
价格 :
美国496.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类
应用 :
Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: 5 µg, RNA Immunoprecipitation: Assay-Dependent, Western Blot: 1:500-1:1,000
物种 :
人类
抗体亚型 :
IgG
储存 :
-20°C or -80°C if preferred
描述 :
HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re imported.
免疫原 :
Synthetic peptide derived from residues 300 to the C-terminus of Human hnRNP A1.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): 5 µg/mL, Immunoprecipitation: 5 µg, RNA Immunoprecipitation: Assay-Dependent, Western Blot: 1:500-1:1,000
别名 :
ALS19; ALS20; Fli-2; Hdp; HDP-1; Helix-destabilizing protein; heterogeneous nuclear ribonucleoprotein A1; Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed; heterogeneous nuclear ribonucleoprotein A1B protein; heterogeneous nuclear ribonucleoprotein B2 protein; heterogeneous nuclear ribonucleoprotein core protein A1; hnRNP A1; hnRNP A1-like 3; hnRNP core protein A1; hnRNP core protein A1-like 3; hnRNP I; Hnrnpa1; hnRNP-A1; HNRNPI; HNRNP-I; Hnrpa1; HNRPA1L3; HNRPA1MGC102835; HNRPI; I79_022927; IBMPFD3; MGC102835; MGC128297 protein; nuclear ribonucleoprotein particle A1 protein; pPTB; PTB; PTB-1; PTB2; PTB3; PTB4; PTB-T; putative heterogeneous nuclear ribonucleoprotein A1-like 3; Putative heterogeneous nuclear ribonucleoprotein A1-like protein 3; ROA1; RP11-78J21.1; single-strand DNA-binding protein UP1; single-strand RNA-binding protein; Single-strand-binding protein; Tis; Topoisomerase-inhibitor suppressed; unwinding protein 1; UP 1; UP1
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公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国