产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
E钙粘蛋白多克隆抗体
目录 :
PA5-19479
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 5
参考文献
Le Roux M, Ollivier A, Kervoaze G, Beke T, Gillet L, Pichavant M, et al. IL-20 Cytokines Are Involved in Epithelial Lesions Associated with Virus-Induced COPD Exacerbation in Mice. Biomedicines. 2021;9: pubmed 出版商
Xu Y, Zuo W, Wang X, Zhang Q, Gan X, Tan N, et al. Deciphering the effects of PYCR1 on cell function and its associated mechanism in hepatocellular carcinoma. Int J Biol Sci. 2021;17:2223-2239 pubmed 出版商
Pardyak L, Kaminska A, Brzoskwinia M, Hejmej A, Kotula Balak M, Jankowski J, et al. Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen. Poult Sci. 2020;99:555-566 pubmed 出版商
Reinartz R, Wang S, Kebir S, Silver D, Wieland A, Zheng T, et al. Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma. Clin Cancer Res. 2017;23:562-574 pubmed 出版商
Chiang M, Hallman S, Cinquin A, de Mochel N, Paz A, Kawauchi S, et al. Analysis of in vivo single cell behavior by high throughput, human-in-the-loop segmentation of three-dimensional images. BMC Bioinformatics. 2015;16:397 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
E钙粘蛋白多克隆抗体
目录# :
PA5-19479
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 1 µg/mL
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20°C or -80°C if preferred
描述 :
E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
免疫原 :
Synthetic peptide conjugated to KLH derived from within residues 850 to the C-terminus of Human pan Cadherin.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 2 µg/mL, Immunohistochemistry (Paraffin): 1 µg/mL, Western Blot: 1 µg/mL
别名 :
AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; Um; UVO; Uvomorulin
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国