产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
NOTCH3多克隆抗体
目录 :
PA5-19515
规格 :
100微克
价格 :
美国456.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
Western blot analysis of K562 Whole Cell Lysate using PA5-19515, NOTCH3 primary antibody at a dilution of 1 ug/ml. Blot treated with a secondary HRP-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:3000.
产品信息
产品类型 :
抗体
产品名称 :
NOTCH3多克隆抗体
目录# :
PA5-19515
规格 :
100微克
价格 :
美国456.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunohistochemistry (PFA fixed): Assay-Dependent, Western Blot: 1 µg/mL
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction (with its cell-bound ligands delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human. NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
免疫原 :
Synthetic peptide conjugated to KLH derived from within residues 2300 to the C-terminus of Human NOTCH3.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-dependent, Immunohistochemistry (PFA fixed): Assay-Dependent, Western Blot: 1 µg/mL
别名 :
AW229011; CADASIL; CADASIL1; CASIL; hpbk; IMF2; LMNS; N3; Neurogenic locus notch homolog protein 3; notch 3; Notch 3 extracellular truncation; Notch 3 intracellular domain; Notch gene homolog 3; Notch homolog 3; NOTCH3
更多信息或购买 :
公司信息
赛默飞世尔