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抗体

半胱天冬酶1多克隆抗体

PA5-20113

100微克

美国446.00

多克隆

domestic rabbit

未共轭

免疫印迹, 免疫组化

半胱天冬酶1多克隆抗体

PA5-20113

100微克

美国446.00

多克隆

抗原亲和色谱

兔

人类

Immunohistochemistry: 10 µg/mL, Western Blot: 0.5-2 µg/mL

人类

IgG

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.

A 15 amino acid peptide from near the middle of human Caspase-1.

液体

Immunohistochemistry: 10 µg/mL, Western Blot: 0.5-2 µg/mL

CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase1; caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL1BC; IL-1BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45