产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IFN乙多克隆抗体
目录 :
PA5-20390
规格 :
100微克
价格 :
美国456.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 图 7c
Ka N, Lim G, Kim S, Hwang S, Han J, Lee Y, et al. Type I IFN stimulates IFI16-mediated aromatase expression in adipocytes that promotes E2-dependent growth of ER-positive breast cancer. Cell Mol Life Sci. 2022;79:306 pubmed 出版商
C xf3 rdoba David G, Garc xed a Gim xe9 nez J, Cardoso Castelo Branco R, Carrasco S, Cannata P, Ortiz A, et al. Crosstalk between TBK1/IKKε and the type I interferon pathway contributes to tubulointerstitial inflammation and kidney tubular injury. Front Pharmacol. 2022;13:987979 pubmed 出版商
Ge X, Wang Y, Xie H, Li R, Zhang F, Zhao B, et al. 1,25(OH)2 D3 blocks IFNβ production through regulating STING in epithelial layer of oral lichen planus. J Cell Mol Med. 2022;26:3751-3759 pubmed 出版商
Lan X, Zhang W, Zhu J, Huang H, Mo K, Guo H, et al. dsRNA Induced IFNβ-MMP13 Axis Drives Corneal Wound Healing. Invest Ophthalmol Vis Sci. 2022;63:14 pubmed 出版商
Ka N, Lim G, Hwang S, Kim S, Lee M. IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer. Cell Rep. 2021;37:110138 pubmed 出版商
Urabe A, Doi S, Nakashima A, Ike T, Morii K, Sasaki K, et al. Klotho deficiency intensifies hypoxia-induced expression of IFN-α/β through upregulation of RIG-I in kidneys. PLoS ONE. 2021;16:e0258856 pubmed 出版商
Broad R, Jones S, Teske M, Wastall L, Hanby A, Thorne J, et al. Inhibition of interferon-signalling halts cancer-associated fibroblast-dependent protection of breast cancer cells from chemotherapy. Br J Cancer. 2021;124:1110-1120 pubmed 出版商
Liang J, Wang H, Ding W, Huang J, Zhou X, Wang H, et al. Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity. Sci Adv. 2020;6:eabc3646 pubmed 出版商
Shao S, Tsoi L, Sarkar M, Xing X, Xue K, Uppala R, et al. IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus. Sci Transl Med. 2019;11: pubmed 出版商
Mukherjee P, Hough G, Chattopadhyay A, Navab M, Fogelman H, Meriwether D, et al. Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum. J Lipid Res. 2017;58:1636-1647 pubmed 出版商
Downey J, Pernet E, Coulombe F, Allard B, Meunier I, Jaworska J, et al. RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection. PLoS Pathog. 2017;13:e1006326 pubmed 出版商
Demaria O, de Gassart A, Coso S, Gestermann N, Di Domizio J, Flatz L, et al. STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity. Proc Natl Acad Sci U S A. 2015;112:15408-13 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA5-20390 图像 1
Immunohistochemical staining of human liver tissue using PA5-20390 anti-IFN-b antibody at a concentration of 5 ug/mL.
图像 2 :
赛默飞世尔 PA5-20390 图像 2
Western blot analysis of IFN-b in A-20 cell lysate with IFN-b antibody at 5 ug/mL.
产品信息
产品类型 :
抗体
产品名称 :
IFN乙多克隆抗体
目录# :
PA5-20390
规格 :
100微克
价格 :
美国456.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
Immunohistochemistry: 2.5 µg/mL, Western Blot: 5 µg/mL
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
4° C
描述 :
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
免疫原 :
A 17来自人中间区域的氨基酸肽段IFN-b
格式 :
液体
应用w/稀释 :
Immunohistochemistry: 2.5 µg/mL, Western Blot: 5 µg/mL
别名 :
Fibroblast interferon; Ifb; IFF; IFN b; IFN ß; IFNB; Ifnb1; IFNbeta; IFN-beta; IFNß; Interferon b; Interferon beta; interferon beta 1; interferon beta 1, fibroblast; interferon beta protein; interferon, beta 1; interferon, beta 1, fibroblast; interferon-beta; RP11-113D19.1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国