产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GRIK1多克隆抗体
目录 :
PA5-20447
规格 :
100微克
价格 :
美国436.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
图像
图像 1 :
Immunohistochemical staining of human brain tissue using PA5-20447 anti-Grik1 antibody at a concentration of 2.5 ug/mL.
图像 2 :
Western blot analysis of Grik1 in P815 cell lysate with Grik1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.
产品信息
产品类型 :
抗体
产品名称 :
GRIK1多克隆抗体
目录# :
PA5-20447
规格 :
100微克
价格 :
美国436.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
Immunohistochemistry: 2.5 µg/mL, Western Blot: 0.5-2 µg/mL
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
描述 :
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. Numerous isoforms of Grik1 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow.
免疫原 :
A 15人近羧基末端的氨基酸肽段Grik1
格式 :
液体
应用w/稀释 :
Immunohistochemistry: 2.5 µg/mL, Western Blot: 0.5-2 µg/mL
别名 :
A830007B11Rik; D16Ium24; D16Ium24e; EAA3; EEA3; excitatory amino acid receptor 3; GLR5; GluK1; GluK5; GLUR5; gluR-5; Glurbeta1; glutamate ionotropic receptor kainate type subunit 1; glutamate receptor; glutamate receptor 5; Glutamate receptor ionotropic, kainate 1; glutamate receptor subunit 5; glutamate receptor, ionotropic, kainate 1; GRIK1
更多信息或购买 :
公司信息
赛默飞世尔