产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
JPH4多克隆抗体
目录 :
PA5-20645
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
图像
图像 1 :
Western blot analysis of JPH4 in 293 cell lysate with JPH4 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
图像 2 :
Immunohistochemical staining of human brain tissue using PA5-20645 anti-JPH4 antibody at a concentration of 2.5 ug/mL.
产品信息
产品类型 :
抗体
产品名称 :
JPH4多克隆抗体
目录# :
PA5-20645
规格 :
100微克
价格 :
美国446.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunohistochemistry: 2.5 µg/mL, Western Blot: 1 µg/mL
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
描述 :
Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain. In the CNS, both JPH3 and JPH4 are expressed throughout neural sites and contribute to the subsurface cistern formation in neurons. Mice lacking both JPH3 and JPH4 subtypes exhibit serious symptoms such as impaired learning and memory and are accompanied by abnormal nervous functions.
免疫原 :
A 16人近羧基末端的氨基酸肽段JPH4
格式 :
液体
应用w/稀释 :
Immunohistochemistry: 2.5 µg/mL, Western Blot: 1 µg/mL
别名 :
9330157P13Rik; JP4; JP-4; Jph4; jph4 {ECO:0000312; JPHL1; junctophilin 4; junctophilin like 1; junctophilin-4; Junctophilin-like 1 protein; KIAA1831; RGD:1303170}
更多信息或购买 :
公司信息
赛默飞世尔