产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ZEB2多克隆抗体
目录 :
PA5-20980
规格 :
100微克
价格 :
美国450.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 6
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 1
Lee E, Wang J, Yumoto K, Jung Y, Cackowski F, Decker A, et al. DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis. Neoplasia. 2016;18:553-66 pubmed 出版商
Gula G, Ruminski S, Niderla Bielinska J, Jasińska A, Kiernozek E, Jankowska Steifer E, et al. Potential functions of embryonic cardiac macrophages in angiogenesis, lymphangiogenesis and extracellular matrix remodeling. Histochem Cell Biol. 2021;155:117-132 pubmed 出版商
Nishad R, Meshram P, Singh A, Reddy G, Pasupulati A. Activation of Notch1 signaling in podocytes by glucose-derived AGEs contributes to proteinuria. BMJ Open Diabetes Res Care. 2020;8: pubmed 出版商
Nishad R, Mukhi D, Tahaseen S, Mungamuri S, Pasupulati A. Growth hormone induces Notch1 signaling in podocytes and contributes to proteinuria in diabetic nephropathy. J Biol Chem. 2019;294:16109-16122 pubmed 出版商
DaSilva Arnold S, Kuo C, Davra V, Remache Y, Kim P, Fisher J, et al. ZEB2, a master regulator of the epithelial-mesenchymal transition, mediates trophoblast differentiation. Mol Hum Reprod. 2019;25:61-75 pubmed 出版商
Ransom R, Carter A, Salhotra A, Leavitt T, Marecic O, Murphy M, et al. Mechanoresponsive stem cells acquire neural crest fate in jaw regeneration. Nature. 2018;563:514-521 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA5-20980 图像 1
Western blot analysis of Jurkat cell lysate using PA5-20980 anti-ZEB2 antibody at (A) 1 and (B) 2ug/mL.
图像 2 :
赛默飞世尔 PA5-20980 图像 2
Immunocytochemistry of Jurkat cells using PA5-20980 anti-ZEB2 antibody at a concentration of 20 ug/mL.
产品信息
产品类型 :
抗体
产品名称 :
ZEB2多克隆抗体
目录# :
PA5-20980
规格 :
100微克
价格 :
美国450.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 20 µg/mL, Western Blot: 1-2 µg/mL
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
描述 :
ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro. ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression. Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that its localization may be regulated in normal and tumor tissues. Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome.
免疫原 :
An 18 amino acid peptide near the carboxy terminus of human ZEB2.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 20 µg/mL, Western Blot: 1-2 µg/mL
别名 :
9130203F04Rik; D130016B08Rik; HRIHFB2411; HSPC082; KIAA0569; SIP1; SIP-1; SMAD interacting protein 1; smad-interacting protein 1; SMADIP1; Zeb2; ZFHX1B; Zfx1b; Zfxh1b; zinc finger E-box binding homeobox 2; zinc finger E-box-binding homeobox 2; zinc finger homeobox 1b; zinc finger homeobox protein 1b
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国