产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
LC3A/LC3B多克隆抗体, HRP
目录 :
PA5-22732
规格 :
100微升
价格 :
美国413.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
HRP
反应物种 :
人类, 小鼠, 大鼠, , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
赛默飞世尔 PA5-22732 图像 1
图像 2 :
赛默飞世尔 PA5-22732 图像 2
产品信息
产品类型 :
抗体
产品名称 :
LC3A/LC3B多克隆抗体, HRP
目录# :
PA5-22732
规格 :
100微升
价格 :
美国413.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
狗, 人类, 小鼠, 大鼠, 斑马鱼
应用 :
Immunohistochemistry (Paraffin): 1:200-1:400, Western Blot: 2 µg/mL
物种 :
狗, 人类, 小鼠, 大鼠, 斑马鱼
抗体亚型 :
IgG
储存 :
4° C, store in dark
描述 :
Autophagy is a process of intracellular bulk degradation in which cytoplasmic components, including organelles, are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. During macroautophagy, the sequestering vesicles, termed autophagosomes, fuse with the lysosome or vacuole resulting in the delivery of an inner vesicle (autophagic body) into the lumen of the degradative compartment. There are 16 proteins participating in the autophagy pathway in human. The autophagy protein LC3, a mammalian homologue of Atg8, was originally identified as microtubule-associated protein 1 light chain 3. It is a component of both the MAP1A and MAP1B microtubule-binding domains and the heavy-chain independent regulation of LC3 expression might modify MAP1 microtubule-binding activity during development. LC3 is the only known mammalian protein identified that stably associates with the autophagosome membranes. LC3-I is cytosolic and LC3-II is membrane bound and enriched in the autophagic vacuole fraction. The detection of LC3-I to LC3-II conversion is a useful and sensitive marker for distinguishing autophagy in mammalian cells.
免疫原 :
A synthetic peptide made to an internal portion of the human LC3 protein sequence (between residues 25-121).
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:200-1:400, Western Blot: 2 µg/mL
别名 :
1010001C15Rik; 1010001H21Rik; 4922501H04Rik; Atg8; ATG8E; ATG8F; Autophagy-related protein LC3 A; autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 A; autophagy-related ubiquitin-like modifier LC3 B; LC3; LC3a; LC3b; MAP1 light chain 3-like protein 1; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 A; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 A; MAP1A/MAP1B light chain 3 B; Map1alc3; MAP1BLC3; Map1lc3; Map1lc3a; MAP1LC3B; MAP1LC3B-a; microtubule associated protein 1 light chain 3 alpha; microtubule associated protein 1 light chain 3 beta; microtubule-associated protein 1 light chain 3; microtubule-associated protein 1 light chain 3 alpha; Microtubule-associated protein 1 light chain 3 beta; microtubule-associated protein 1-light chain 3A; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3A; Microtubule-associated proteins 1A/1B light chain 3B; Mpl3; wu:fb60g11; zbs559; zgc:56434; zgc:77094
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国