产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
SPHK1多克隆抗体
目录 :
PA5-22994
规格 :
100微克
价格 :
美国500.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
图像
图像 1 :
产品信息
产品类型 :
抗体
产品名称 :
SPHK1多克隆抗体
目录# :
PA5-22994
规格 :
100微克
价格 :
美国500.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 大鼠
应用 :
Immunocytochemistry: 1:100, Immunoprecipitation: 5-15 µg/mg lysate, Western Blot: 1:2,000-1:10,000
物种 :
人类, 大鼠
抗体亚型 :
IgG
储存 :
4° C, 不冻结
描述 :
SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer. SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).
免疫原 :
The epitope recognized by this antibody maps to a region between residue 334-384 of human sphingosine kinase 1 using the numbering given in entry NP_001136073.1
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100, Immunoprecipitation: 5-15 µg/mg lysate, Western Blot: 1:2,000-1:10,000
别名 :
1110006G24Rik;乙酰转移酶类SPHK1;RP23-193A16.4;SK 1;Sk1;SKase;鞘氨醇激酶1;SPHK;SPHK1;SPK;SPK 1;Spk1
更多信息或购买 :
公司信息
赛默飞世尔