产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
RAD51多克隆抗体
目录 :
PA5-27195
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
fission yeast, 人类, 小鼠, 大鼠, 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 4i
  • 免疫印迹; 小鼠; 图 2f
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, et al. The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells. Nat Commun. 2020;11:2055 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 s6c
Liu H, Huang T, Li M, Li M, Zhang C, Jiang J, et al. SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice. Nucleic Acids Res. 2019;47:5670-5683 pubmed 出版商
  • 免疫细胞化学; fission yeast; 1:100; 图 7d
Manjón E, Edreira T, Muñoz S, Sanchez Y. Rgf1p (Rho1p GEF) is required for double-strand break repair in fission yeast. Nucleic Acids Res. 2017;45:5269-5284 pubmed 出版商
Tesfay L, Paul B, Hegde P, Brewer M, Habbani S, JELLISON E, et al. Complementary anti-cancer pathways triggered by inhibition of sideroflexin 4 in ovarian cancer. Sci Rep. 2022;12:19936 pubmed 出版商
Shang Y, Huang J, Li W, Zhang Y, Zhou X, Shao Q, et al. MEIOK21 regulates oocyte quantity and quality via modulating meiotic recombination. FASEB J. 2022;36:e22357 pubmed 出版商
Qin J, Huang T, Wang J, Xu L, Dang Q, Xu X, et al. RAD51 is essential for spermatogenesis and male fertility in mice. Cell Death Discov. 2022;8:118 pubmed 出版商
Moore S, Narayanan D, Simonette R, Bartley B, Doan H, Rady P, et al. Selinexor is a novel inhibitor of DNA damage response in Merkel cell carcinoma. Clin Exp Dermatol. 2022;47:1354-1357 pubmed 出版商
Klomp J, Lee Y, Goodwin C, Papke B, Klomp J, Waters A, et al. CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment. Cell Rep. 2021;37:110060 pubmed 出版商
Liu Y, Yang C, Zhang Z, Jiang H. Gut Microbiota Dysbiosis Accelerates Prostate Cancer Progression Through Increased LPCAT1 Expression and Enhanced DNA Repair Pathways. Front Oncol. 2021;11:679712 pubmed 出版商
Silva V, Saxena J, Nicolini F, Hoare J, Metcalf S, Martin S, et al. Chloroxine overrides DNA damage tolerance to restore platinum sensitivity in high-grade serous ovarian cancer. Cell Death Dis. 2021;12:395 pubmed 出版商
Shang Y, Huang T, Liu H, LIU Y, Liang H, Yu X, et al. MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis. Nucleic Acids Res. 2020;48:6624-6639 pubmed 出版商
Huang T, Yuan S, Gao L, Li M, Yu X, Zhang J, et al. The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair. elife. 2020;9: pubmed 出版商
Zhang J, Fujiwara Y, Yamamoto S, Shibuya H. A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination. Nat Commun. 2019;10:722 pubmed 出版商
Dasgupta Y, Golovine K, Nieborowska Skorska M, Luo L, Matlawska Wasowska K, Mullighan C, et al. Drugging DNA repair to target T-ALL cells. Leuk Lymphoma. 2018;59:1746-1749 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA5-27195 图像 1
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft using Rad51 (PA5-27195) antibody at 1:100 dilution.
图像 2 :
赛默飞世尔 PA5-27195 图像 2
Immunofluorescence analysis of paraformaldehyde-fixed HeLa cells using Rad51 (PA5-27195) antibody at 1:200 dilution.
图像 3 :
赛默飞世尔 PA5-27195 图像 3
Western Blot analysis of Rad51 using anti-Rad51 Polyclonal Antibody (PA5-27195), in NIH-3T3 Cell Lysate (30 ug of cell lysate) and at a dilution of 1:1000.
产品信息
产品类型 :
抗体
产品名称 :
RAD51多克隆抗体
目录# :
PA5-27195
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠, 斑马鱼
应用 :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000
物种 :
人类, 小鼠, 大鼠, 斑马鱼
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
免疫原 :
Recombinant fragment corresponding to a region within amino acids 1 and 228 of Human Rad51
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000
别名 :
AV304093; BRCA1/BRCA2-containing complex, subunit 5; BRCC5; DNA repair protein RAD51; DNA repair protein RAD51 homolog 1; DNA repair protein RAD51 homolog A; DNA repair protein rhp51; FANCR; homolog to S.cerevisiae; HRAD51; HsRad51; HsT16930; MGC128559 protein; MRMV2; MUT5; rad51; RAD51 homolog; RAD51 homolog (RecA homolog); RAD51 homolog (RecA homolog, E. coli); RAD51 homolog A; RAD51 recombinase; RAD51 recombinase L homeolog; rad51.1; rad51.L; rad51-1; RAD51A; rad51-a; rad51-b; Reca; RecA family recombinase Rhp51; RecA, E. coli, homolog of; RecA-like protein; recombinase RAD51; recombination protein A; RGD1563603; rhp51; SPAC644.14c; wu:fb38e12; xrad51; XRad51.1; YER095W; zgc:77754
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国