产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TDG多克隆抗体
目录 :
PA5-29140
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
文章摘录数: 2
参考文献
Müller N, Ponkkonen E, Carell T, Khobta A. Direct and Base Excision Repair-Mediated Regulation of a GC-Rich cis-Element in Response to 5-Formylcytosine and 5-Carboxycytosine. Int J Mol Sci. 2021;22: pubmed 出版商
Kolendowski B, Hassan H, Krstic M, Isovic M, Thillainadesan G, Chambers A, et al. Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization. Epigenetics Chromatin. 2018;11:5 pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA5-29140 图像 1
Western Blot analysis using anti-TDG Polyclonal Antibody on the following cells: (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa. Primary antibody (PA5-29140) diluted at 1:5000
产品信息
产品类型 :
抗体
产品名称 :
TDG多克隆抗体
目录# :
PA5-29140
规格 :
100微升
价格 :
美国496.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类
应用 :
Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:5,000-1:20,000
物种 :
人类
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mis paired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
免疫原 :
Recombinant protein fragment corresponding to a region within amino acids 1 and 410 of Human TDG
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:5,000-1:20,000
别名 :
C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国