产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TUBA1A多克隆抗体
目录 :
PA5-29444
规格 :
100微升
价格 :
美国460.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 10
参考文献
Singh A, Busacca S, Gaba A, Sheaff M, Poile C, Nakas A, et al. BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms. Oncogene. 2022;: pubmed 出版商
Stoiber P, Scribani Rossi P, Pokharel N, Germany J, York E, Schaus S, et al. Factor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules. Sci Rep. 2021;11:23564 pubmed 出版商
Sakowicz A, Bralewska M, Pietrucha T, Figueras F, Habrowska G xf3 rczy x144 ska D, Piastowska Ciesielska A, et al. The Preeclamptic Environment Promotes the Activation of Transcription Factor Kappa B by P53/RSK1 Complex in a HTR8/SVneo Trophoblastic Cell Line. Int J Mol Sci. 2021;22: pubmed 出版商
Kim H, Lee J, Kim S, Lee S, Jung D, Williams D. Investigation of niclosamide as a repurposing agent for skeletal muscle atrophy. PLoS ONE. 2021;16:e0252135 pubmed 出版商
Lee J, Kim S, Kim J, Kim H, Um J, Jung D, et al. Lithium Chloride Protects against Sepsis-Induced Skeletal Muscle Atrophy and Cancer Cachexia. Cells. 2021;10: pubmed 出版商
Selyutina A, Persaud M, Lee K, KEWALRAMANI V, Diaz Griffero F. Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating. Cell Rep. 2020;32:108201 pubmed 出版商
Kostrzewska Poczekaj M, Bednarek K, Jarmuz Szymczak M, Bodnar M, Filas V, Marszalek A, et al. Copy number gains of the putative CRKL oncogene in laryngeal squamous cell carcinoma result in strong nuclear expression of the protein and influence cell proliferation and migration. Sci Rep. 2020;10:24 pubmed 出版商
Piekarowicz K, Bertrand A, Azibani F, Beuvin M, Julien L, Machowska M, et al. A Muscle Hybrid Promoter as a Novel Tool for Gene Therapy. Mol Ther Methods Clin Dev. 2019;15:157-169 pubmed 出版商
Lukacs M, Gilley J, Zhu Y, Orsomando G, Angeletti C, Liu J, et al. Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence. Exp Neurol. 2019;320:112961 pubmed 出版商
Dubińska Magiera M, Kozioł K, Machowska M, Piekarowicz K, Filipczak D, Rzepecki R. Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients. Cells. 2019;8: pubmed 出版商
图像
图像 1 :
赛默飞世尔 PA5-29444 图像 1
Western Blot analysis using anti-alpha Tubulin 4a Polyclonal Antibody on the following cells: (30 ug of whole cell lysate) A: Jurkat B: Raji C: 293T D: A431 E: HeLa F: HepG2 G: H1299 H: HCT116 I: MCF-7 J: NT2D1 K: PC-3 L: U87-MG. Primary antibody (PA5-29444) diluted at 1:10000
图像 2 :
赛默飞世尔 PA5-29444 图像 2
Confocal immunofluorescence analysis of methanol-fixed HeLa using alpha Tubulin 4a (PA5-29444) antibody (green) at 1:500 dilution. Alpha-tubulin filaments were labeled with MA1-25054 (red) at 1:2500.
图像 3 :
赛默飞世尔 PA5-29444 图像 3
Immunohistochemical analysis of paraffin-embedded U373 xenograft using alpha Tubulin 4a (PA5-29444) antibody at 1:500 dilution.
产品信息
产品类型 :
抗体
产品名称 :
TUBA1A多克隆抗体
目录# :
PA5-29444
规格 :
100微升
价格 :
美国460.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
Chicken, Drosophila, Human, Insect, Mouse, Non-human primate, Rat
应用 :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:20,000
物种 :
Chicken, Drosophila, Human, Insect, Mouse, Non-human primate, Rat
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
免疫原 :
Recombinant protein encompassing a sequence within the center region of human alpha Tubulin. The exact sequence is proprietary.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:20,000
别名 :
alpha 1a antibody; alpha 3 antibody; alpha-tubulin; alpha-tubulin 1; Alpha-tubulin 3; alpha-tubulin 3 antibody; Alpha-tubulin isotype M-alpha-1; B-ALPHA-1; B-ALPHA-1 antibody; brain-specific antibody; Detyrosinated tubulin alpha-1A chain; FLJ25113 antibody; FLJ30169; H2 ALPHA; H2ALPHA; H2-ALPHA; hum-a-tub1; hum-a-tub1 antibody; hum-a-tub2; hum-a-tub2 antibody; LIS3; LIS3 antibody; LOC106557476; M40; MGC117247; MGC16435; OK/SW cl.56; OK/SWcl.56; OK/SW-cl.56; Talpha1 alpha-tubulin; TUBA1; Tuba-1; Tuba1a; TUBA1A antibody; TUBA3; TUBA3 antibody; TUBA6; TUBB1; TUBB5; tubulin alpha 1a; tubulin alpha-1 chain; Tubulin alpha-1A chain; tubulin alpha-1A chain antibody; tubulin alpha-3 chain; tubulin alpha-3 chain antibody; Tubulin B-alpha-1; tubulin B-alpha-1 antibody; tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1A; tubulin, alpha 6; tubulin, alpha, brain-specific; unnamed protein product
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国