产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
GNB1多克隆抗体
目录 :
PA5-30046
规格 :
100微升
价格 :
美国450.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
赛默飞世尔 PA5-30046 图像 1
Immunofluorescence analysis of methanol-fixed HeLa cells using GNB1 (PA5-30046) antibody at 1:200 dilution.
图像 2 :
赛默飞世尔 PA5-30046 图像 2
Immunohistochemical analysis of paraffin-embedded Lung papillory AdCA using GNB1 (PA5-30046) antibody at 1:500 dilution.
图像 3 :
赛默飞世尔 PA5-30046 图像 3
Western Blot analysis of GNB1 using anti-GNB1 Polyclonal Antibody (PA5-30046), in Mouse Brain (50 ug of cell lysate) and at a dilution of 1:10000.
产品信息
产品类型 :
抗体
产品名称 :
GNB1多克隆抗体
目录# :
PA5-30046
规格 :
100微升
价格 :
美国450.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:1,000-1:10,000
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Vision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain. The process of converting light into an electrochemical signal begins when the membrane-bound protein, rhodopsin, absorbs light within the retina. Photoexcitation of rhodopsin causes the cytoplasmic surface of the protein to become catalytically active. In the active state, rhodopsin activates transducin, a GTP binding protein. Once activated, transducin promotes the hydrolysis of cGMP by phosphodiesterase (PDE). The decrease of intracellular cGMP concentration causes the ion channels within the outer segment of the rod or cone to close, thus causing membrane hyperpolarization and, eventually, signal transmission. Rhodopsin activity is believed to be shut off by phosphorylation followed by binding of the soluble protein, arrestin. Transducin, once activated by rhodopsin, promotes the hydrolysis of cGMP by PDE. The subunit composition of transducin differs between different photoreceptor cells. Rod transducin consists of rod transducin alpha (Tr alpha), T beta, and T gamma. Cone transducin is composed of cone transducin alpha (Tc alpha), T beta and T gamma. Differential transducin subunit composition of transducin is believed to be responsible for the different light sensitivities between photoreceptive cells.
免疫原 :
Recombinant protein fragment corresponding to a region within amino acids 67 and 271 of Human GNB1
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:1,000-1:10,000
别名 :
AA409223; beta subunit, signal-transducing proteins GS/GI; C77571; G protein subunit beta 1; gbb1; GNB1; Gnb-1; gnb1 protein; gnb1a; guanine nucleotide binding protein (G protein), beta 1; guanine nucleotide binding protein (G protein), beta polypeptide 1; guanine nucleotide binding protein (G protein), beta polypeptide 1a; guanine nucleotide binding protein, beta 1; Guanine nucleotide-binding protein beta 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; guanine nucleotide-binding protein, beta-1 subunit; MRD42; T beta; testicular tissue protein Li 72; transducin beta chain 1; transducin beta subunit; unnamed protein product; wu:fb50b09; wu:fj94h04
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国