E钙粘蛋白多克隆抗体 | 赛默飞世尔 PA5-32178 产品信息

产品简要

公司名称 :

赛默飞世尔

其他品牌 :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

产品类型 :

抗体

产品名称 :

E钙粘蛋白多克隆抗体

PA5-32178

规格 :

100微升

价格 :

美国510.00

克隆性 :

多克隆

宿主 :

domestic rabbit

共轭标签 :

未共轭

反应物种 :

人类, 大鼠

应用 :

免疫印迹, 免疫细胞化学, 免疫沉淀

更多信息或购买 :

赛默飞世尔产品网页

文章摘录数: 12

参考文献
Shang J, Lin L, Huang X, Zhou L, Huang Q. Re-expression of circ_0043610 contributes to trophoblast dysfunction through the miR-558/RYBP pathway in preeclampsia. Endocr J. 2022;69:1373-1385 pubmed 出版商
Wang H, Luo Y, Chu Z, Ni T, Ou S, Dai X, et al. Poria Acid, Triterpenoids Extracted from Poria cocos, Inhibits the Invasion and Metastasis of Gastric Cancer Cells. Molecules. 2022;27: pubmed 出版商
Li D, Fu Z, Dong C, Song Y. Downregulation of circATXN7 represses non-small cell lung cancer growth by releasing miR-7-5p. Thorac Cancer. 2022;13:1597-1610 pubmed 出版商
Chu Z, Luo Y, Ni T, Zhu M, Feng X, Liu Y, et al. Betulonic Acid, as One of the Active Components of the Celastrus orbiculatus Extract, Inhibits the Invasion and Metastasis of Gastric Cancer Cells by Mediating Cytoskeleton Rearrangement In Vitro. Molecules. 2022;27: pubmed 出版商
Abraham H, Ulintz P, Goo L, Yates J, Little A, Bao L, et al. RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers. Front Oncol. 2021;11:712041 pubmed 出版商
Batsche E, Yi J, Mauger O, Kornobis E, Hopkins B, Hanmer Lloyd C, et al. CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms. Nucleic Acids Res. 2021;49:6213-6237 pubmed 出版商
Malgundkar S, Burney I, Al Moundhri M, Al Kalbani M, Lakhtakia R, Okamoto A, et al. E2F5 Promotes the Malignancy of Ovarian Cancer Via the Regulation of Hippo and Wnt Pathways. Genet Test Mol Biomarkers. 2021;25:179-186 pubmed 出版商
Malgundkar S, Burney I, Al Moundhri M, Al Kalbani M, Lakhtakia R, Okamoto A, et al. FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer. BMC Cancer. 2020;20:374 pubmed 出版商
Sim J, Jeong K. Monitoring Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells via Investigation of Mitochondrial Dysfunction. Methods Protoc. 2020;3: pubmed 出版商
Funfak A, Bouzhir L, Gontran E, Minier N, Dupuis Williams P, Gobaa S. Biophysical Control of Bile Duct Epithelial Morphogenesis in Natural and Synthetic Scaffolds. Front Bioeng Biotechnol. 2019;7:417 pubmed 出版商
Kao H, Kuo C, Chen K, Chen J. Preparation of Gelatin and Gelatin/Hyaluronic Acid Cryogel Scaffolds for the 3D Culture of Mesothelial Cells and Mesothelium Tissue Regeneration. Int J Mol Sci. 2019;20: pubmed 出版商
Liu J, Ma ayeh S, Peirasmaki D, Lundström Stadelmann B, Hellman L, Svard S. Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines. Virulence. 2018;9:879-894 pubmed 出版商

图像

图像 1 :

Confocal immunofluorescence analysis of methanol-fixed A431 using E-cadherin (PA5-32178) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with MA1-25054 (Red) at 1:2000.

图像 2 :

Western Blot analysis of E-cadherin using anti-E-cadherin Polyclonal Antibody (PA5-32178), in 293T Cell (30 ug of cell lysate) and at a dilution of 1:3000.

产品信息

产品类型 :

抗体

产品名称 :

E钙粘蛋白多克隆抗体

目录# :

PA5-32178

规格 :

100微升

价格 :

美国510.00

克隆性 :

多克隆

纯度 :

抗原亲和色谱

宿主 :

兔

反应物种 :

人类, 大鼠

应用 :

Immunocytochemistry: 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:10,000

物种 :

人类, 大鼠

抗体亚型 :

IgG

储存 :

短期存放在4°C。为长期储存, 存放在-20°C, 避免反复冷冻/解冻

描述 :

E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

免疫原 :

Recombinant fragment corresponding to a region within amino acids 338 and 649 of Human E-cadherin

格式 :

液体

应用w/稀释 :

Immunocytochemistry: 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:10,000

别名 :

AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; Um; UVO; Uvomorulin

更多信息或购买 :

赛默飞世尔产品网页

公司信息

赛默飞世尔

上海浦东新金桥路27号7号楼

analyze.cn@thermofisher.com

http://www.thermo.com.cn

1084193588

公司总部: 美国