NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

LC3A(切断的Gly120)多克隆抗体

PA5-35196

400微升

美国456.00

多克隆

domestic rabbit

未共轭

人类, 小鼠

免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片

LC3A(切断的Gly120)多克隆抗体

PA5-35196

400微升

美国456.00

多克隆

抗原亲和色谱, 蛋白质A

兔

人类, 小鼠

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:10-1:50, Immunohistochemistry (PFA fixed): 1:100, Western Blot: 1:1,000

人类, 小鼠

IgG

-20° C, 避免反复冷冻/解冻

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3a is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.

KLH conjugated synthetic peptide between 89-120 amino acids from human Cleaved LC3A

液体

Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:10-1:50, Immunohistochemistry (PFA fixed): 1:100, Western Blot: 1:1,000

1010001H21Rik; 4922501H04Rik; ATG8E; Autophagy-related protein LC3 A; autophagy-related ubiquitin-like modifier LC3 A; LC3; LC3A; MAP1 light chain 3-like protein 1; MAP1A/1B light chain 3 A; MAP1A/MAP1B LC3 A; MAP1A/MAP1B light chain 3 A; MAP1ALC3; MAP1BLC3; MAP1LC3A; microtubule associated protein 1 light chain 3 alpha; Microtubule-associated protein 1 light chain; microtubule-associated protein 1 light chain 3 alpha; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3A