产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化TGFBR1(Ser165)多克隆抗体
目录 :
PA5-40298
规格 :
100微升
价格 :
美国436.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 7
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:500; 图 7c
Humeres C, Shinde A, Hanna A, Alex L, Hern xe1 ndez S, Li R, et al. Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure. J Clin Invest. 2022;132: pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 5c
Yang L, Han B, Zhang M, Wang Y, Tao K, Zhu M, et al. Activation of BK Channels Prevents Hepatic Stellate Cell Activation and Liver Fibrosis Through the Suppression of TGFβ1/SMAD3 and JAK/STAT3 Profibrotic Signaling Pathways. Front Pharmacol. 2020;11:165 pubmed 出版商
Lory W, Wellslager B, Sun C, Yilmaz x, Yu H. Inhibition of Sphingosine-1-Phosphate Receptor 2 by JTE013 Enhanced Alveolar Bone Regeneration by Promoting Angiogenesis. Int J Mol Sci. 2023;24: pubmed 出版商
Milara J, Ballester B, Safont M, Artigues E, Escriv xe1 J, Morcillo E, et al. MUC4 is overexpressed in idiopathic pulmonary fibrosis and collaborates with transforming growth factor β inducing fibrotic responses. Mucosal Immunol. 2021;14:377-388 pubmed 出版商
Ghiroldi A, Piccoli M, Creo P, Cirillo F, Rota P, D Imperio S, et al. Role of sialidase Neu3 and ganglioside GM3 in cardiac fibroblasts activation. Biochem J. 2020;477:3401-3415 pubmed 出版商
Watanabe H, Goto S, Kato R, Komiyama S, Nagaoka Y, Kazama T, et al. The neovascularization effect of dedifferentiated fat cells. Sci Rep. 2020;10:9211 pubmed 出版商
Wang K, Wang X, Hou Y, Zhou H, Mai K, He G. Apoptosis of cancer cells is triggered by selective crosslinking and inhibition of receptor tyrosine kinases. Commun Biol. 2019;2:231 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
磷酸化TGFBR1(Ser165)多克隆抗体
目录# :
PA5-40298
规格 :
100微升
价格 :
美国436.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠, 大鼠
应用 :
ELISA: 1:5,000, Western Blot: 1:500-1:2,000
物种 :
人类, 小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1. TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).
免疫原 :
Synthesized peptide derived from human TGFbeta RI around the phosphorylation site of S165.
格式 :
液体
应用w/稀释 :
ELISA: 1:5,000, Western Blot: 1:500-1:2,000
别名 :
AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国