NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

COL4A5多克隆抗体

PA5-49913

100微升

美国436.00

多克隆

domestic rabbit

未共轭

人类, 小鼠

免疫组化, 免疫细胞化学, 免疫组化-石蜡切片

COL4A5多克隆抗体

PA5-49913

100微升

美国436.00

多克隆

抗原亲和色谱

兔

人类, 小鼠

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:100

人类, 小鼠

IgG

-20°C

Collagens are highly conserved and are characterized by an uninterrupted Glycine-X-Y triplet repeat. Col1, the fibrillar collagen found in most connective tissues, is the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Col2, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia. Col3 is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome type IV, aortic and arterial aneurysms. Col4 is a major consitiuent of the basement membranes along with laminins and enactins. It is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio. Col4 antibodies are useful in detecting the loss of parts of basement membrane in carcinomas. Col5 is found in tissues containing Col1 and appears to regulate the assembly of heterotypic fibers composed of both Col1 and Col5. Col5 is closely related to type XI collagen; mutations in this gene are associated with Ehlers-Danlos syndrome.

Synthesized peptide derived from internal of human Collagen IV alpha5.

液体

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:100

ASLN; ATS; CA54; CO4A5; COL4A5; Collagen alpha-5(IV) chain; collagen IV, alpha-5 polypeptide; collagen of basement membrane, alpha-5 chain; collagen type IV alpha 5 chain; collagen type IV alpha5 chain; collagen, type IV, alpha 5; dA149D17.3; dA24A23.1; procollagen type IV alpha 5; procollagen, type IV, alpha 5