产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
NOX4多克隆抗体
目录 :
PA5-53304
规格 :
100微升
价格 :
美国500
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 1
参考文献
Zheng H, Xu N, Zhang Z, Wang F, Xiao J, Ji X. Setanaxib (GKT137831) Ameliorates Doxorubicin-Induced Cardiotoxicity by Inhibiting the NOX1/NOX4/Reactive Oxygen Species/MAPK Pathway. Front Pharmacol. 2022;13:823975 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
NOX4多克隆抗体
目录# :
PA5-53304
规格 :
100微升
价格 :
美国500
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 0.25-2 µg/mL, Immunofluorescence: 0.25-2 µg/mL, Immunohistochemistry: 1:50-1:200
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Oxygen sensing is essential for homeostasis in all aerobic organisms. A phagocyte-type oxidase, similar to that responsible for the production of large amounts of reactive oxygen species (ROS) in neutrophil granulocytes, with resultant antimicrobial activity, has been postulated to function in the kidney as an oxygen sensor that regulates the synthesis of erythropoietin in the renal cortex. NOX4 has a role as a redox messenger in the activation of intracellular signaling pathways leading (or contributing) to mitochondriogenesis, cell survival, and differentiation in hematopoietic stem cells. Data suggests that NOX4 provides a novel link between the insulin receptor and the generation of cellular reactive oxygen species that enhances insulin signal transduction.
免疫原 :
Recombinant protein corresponding to Human NOX4
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 0.25-2 µg/mL, Immunofluorescence: 0.25-2 µg/mL, Immunohistochemistry: 1:50-1:200
别名 :
AI648021; Kidney oxidase-1; kidney superoxide-producing NADPH oxidase; Kox; KOX1; KOX-1; NADPH oxidase 4; NOX 4; NOX4; NOX-4; renal NAD(P)H-oxidase; RENOX; Superoxide-generating NADPH oxidase 4
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国