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抗体

NOX4多克隆抗体

PA5-72444

100µL

美国345

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠, 犬

免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片

NOX4多克隆抗体

PA5-72444

100µL

美国345

多克隆

selective precipitation

兔

狗, 人类, 小鼠, 大鼠

Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: Assay-Dependent

狗, 人类, 小鼠, 大鼠

IgG

-20°C

Oxygen sensing is essential for homeostasis in all aerobic organisms. A phagocyte-type oxidase, similar to that responsible for the production of large amounts of reactive oxygen species (ROS) in neutrophil granulocytes, with resultant antimicrobial activity, has been postulated to function in the kidney as an oxygen sensor that regulates the synthesis of erythropoietin in the renal cortex. NOX4 has a role as a redox messenger in the activation of intracellular signaling pathways leading (or contributing) to mitochondriogenesis, cell survival, and differentiation in hematopoietic stem cells. Data suggests that NOX4 provides a novel link between the insulin receptor and the generation of cellular reactive oxygen species that enhances insulin signal transduction.

液体

Immunofluorescence: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Western Blot: Assay-Dependent

AI648021; BOS_24390; Kidney oxidase-1; Kidney superoxide-producing NADPH oxidase; Kox; KOX1; KOX-1; NADPH oxidase 4; NOX 4; NOX4; NOX-4; Renal NAD(P)H-oxidase; Renox; Superoxide-generating NADPH oxidase 4