产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PTPN13多克隆抗体
目录 :
PA5-72906
规格 :
50微升
价格 :
美国436.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
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文章摘录数: 1
产品信息
产品类型 :
抗体
产品名称 :
PTPN13多克隆抗体
目录# :
PA5-72906
规格 :
50微升
价格 :
美国436.00
克隆性 :
多克隆
宿主 :
兔
反应物种 :
人类
应用 :
Immunocytochemistry: 1:500-1:3,000, Immunohistochemistry (Frozen): 1:10-1:500, Immunohistochemistry (Paraffin): 1:1,000-1:5,000, Immunoprecipitation: 1:50-1:200, Western Blot: 1:1,000-1:2,000
物种 :
人类
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
免疫原 :
A recombinant protein corresponding to amino acids 1279 to 1883 of human FAP-1 protein was used as immunogen; GenBank no. NP_542414.1.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:500-1:3,000, Immunohistochemistry (Frozen): 1:10-1:500, Immunohistochemistry (Paraffin): 1:1,000-1:5,000, Immunoprecipitation: 1:50-1:200, Western Blot: 1:1,000-1:2,000
别名 :
AI324989; DKFZp686J1497; FAP-1; Fas-associated protein-tyrosine phosphatase 1; hPTP1E; hPTPE1; PNP1; protein Tyr phosphatase; protein tyrosine phosphatase DPZPTP; Protein tyrosine phosphatase PTP-BL; protein tyrosine phosphatase, non-receptor type 13; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase); protein-tyrosine phosphatase 1E; Protein-tyrosine phosphatase PTPL1; protein-tyrosine phosphatase RIP; ptp; Ptp14; PTP1E; PTP36; PTP-BAS; PTP-BL; PTP-E1; PTPL1; PTPLE; PTPN13; Ptpri; RIP; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 13
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公司信息
赛默飞世尔