NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

ERK1多克隆抗体

PA5-77818

100微升

美国486.00

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠, 牛, 家羊

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片

ERK1多克隆抗体

PA5-77818

100微升

美国486.00

多克隆

抗原亲和色谱

兔

Bovine, Chicken, Drosophila, Human, Mouse, Ovine, Rat, Xenopus laevis

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry (PFA fixed): 1:100, Western Blot: 1:5,000

Bovine, Chicken, Drosophila, Human, Mouse, Ovine, Rat, Xenopus laevis

IgG

-20°C

MAPK3 (ERK1) is a serine/threonine kinase that is an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. ERK1 is widely expressed and involved in the regulation of meiosis, mitosis, and post-mitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways. Functionally, ERK1 is involved with a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. ERK1 is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms of ERK1 have been described.

A 35 residue synthetic peptide, corresponding to rat Erk1 MAP kinase with the CGG spacer group added and the peptide coupled to KLH.

液体

Flow Cytometry: Assay-Dependent, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100, Immunohistochemistry (PFA fixed): 1:100, Western Blot: 1:5,000

ERK; Erk1; ERK-1; Ert2; Esrk1; Extracellular signal-regulated kinase 1; extracellular signal-related kinase 1; HS44KDAP; HUMKER1A; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAP kinase2; MAPK 1; MAPK 3; MAPK1; MAPK2; MAPK3; Microtubule-associated protein 2 kinase; mitogen activated protein kinase 3; mitogen-activated 3; mitogen-activated protein kinase 1; mitogen-activated protein kinase 3; MNK1; Mtap2k; p44; p44 MAP kinase; P44ERK1; p44-ERK1; P44MAPK; p44-MAPK; pp42/MAP kinase; PRKM3