NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

YAP1多克隆抗体

PA5-78322

100微升

美国456.00

多克隆

domestic rabbit

未共轭

人类, 斑马鱼

免疫印迹, 免疫沉淀

YAP1多克隆抗体

PA5-78322

100微升

美国456.00

多克隆

抗原亲和色谱

兔

人类, 斑马鱼

Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000

人类, 斑马鱼

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human YAP1. The exact sequence is proprietary.

液体

Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000

65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP