产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
LON多克隆抗体
目录 :
PA5-80261
规格 :
100微升
价格 :
美国169.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
应用 :
酶联免疫吸附测定
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
LON多克隆抗体
目录# :
PA5-80261
规格 :
100微升
价格 :
美国169.00
克隆性 :
多克隆
纯度 :
蛋白质A
宿主 :
兔
反应物种 :
细菌
应用 :
ELISA: 1:1, 000-1:2, 000
物种 :
细菌
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Lon protease is an ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins, including some antitoxins. It is required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Lon protease degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. It binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, UmuD and at least type II antitoxins CcdA, HipB and MazE. Its overproduction specifically inhibits translation through at least two different pathways, one of them being the YoeB-YefM toxin-antitoxin system. Overproduction leads to very high persister cell formation (cells highly resistant to antibiotics), but not when 10 mRNA interferases are deleted, nor when Lon catalytic residues are mutated.
免疫原 :
重组大肠埃希杆菌LON PROTEASE蛋白
格式 :
液体
应用w/稀释 :
ELISA: 1:1, 000-1:2, 000
别名 :
ATP-dependent protease La; capR; deg; muc
更多信息或购买 :
公司信息
赛默飞世尔