NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

CCS多克隆抗体

PA5-83703

100微升

美国456.00

多克隆

domestic rabbit

未共轭

免疫印迹, 免疫组化

CCS多克隆抗体

PA5-83703

100微升

美国456.00

多克隆

Anitgen affinity chromatography, Antigen affinity chromatography

兔

人类

Immunohistochemistry: 1:200-1:500, Western Blot: 0.04-0.4 µg/mL

人类

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.

Recombinant protein corresponding to Human CCS

液体

Immunohistochemistry: 1:200-1:500, Western Blot: 0.04-0.4 µg/mL

CCS; Ccsd; copper chaperone for superoxide dismutase; Superoxide dismutase copper chaperone