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抗体

TPSG1多克隆抗体

PA5-84456

100微升

美国500.00

多克隆

domestic rabbit

未共轭

TPSG1多克隆抗体

PA5-84456

100微升

美国500.00

多克隆

Anitgen affinity chromatography, Antigen affinity chromatography

兔

人类

Immunohistochemistry: 1:200-1:500

人类

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

Tryptase gamma, also known as serine protease 31 or transmembrane tryptase, is an enzyme that in humans is encoded by the TPSG1 gene. Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes -alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.

Recombinant protein corresponding to Human TPSG1

液体

Immunohistochemistry: 1:200-1:500

PRSS31; serine protease 31; TMT; TPSG1; Transmembrane tryptase; trpA; Tryptase gamma; Tryptase- gamma; tryptase gamma 1; Tryptase gamma heavy chain; tryptase gamma I; tryptase gamma II; Tryptase gamma light chain