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抗体

ARHGEF1多克隆抗体

PA5-84467

100微升

美国456.00

多克隆

domestic rabbit

未共轭

免疫印迹, 免疫细胞化学

ARHGEF1多克隆抗体

PA5-84467

100微升

美国456.00

多克隆

Anitgen affinity chromatography, Antigen affinity chromatography

兔

人类

Immunocytochemistry: 0.25-2 µg/mL, Western Blot: 0.04-0.4 µg/mL

人类

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

The Ras superfamily of GTPases, which can be subdivided into the Ras, Rho/Rac, Sar, Rab, ARF and Ran subfamilies, controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. The Ras superfamily of GTPases function as regulated switches that toggle between a biologically active GTP-bound and an inactive GDP-bound form. This activation is catalyzed by guanine nucleotide exchange factors (GEFs). The Dbl-related proteins are a large family of structurally related molecules that have a common ability to catalyze GEF activity for specific members of the Ras family. Dbl-related proteins include FGD1, Lsc, RhoGEF p115, Lfc, Lbc and Brx. Lsc, Lbc and Lfc share sequence homology and show exchange activity toward Rho family GTPases. RhoGEF p115 catalyzes GEF activity for Rho but not Rac, Cdc42 or Ras GTPases.

Recombinant protein corresponding to Human ARHGEF1

液体

Immunocytochemistry: 0.25-2 µg/mL, Western Blot: 0.04-0.4 µg/mL

115 kDa guanine nucleotide exchange factor; 115-kD protein; ARHGEF1; GEF1; LBCL2; Lbc's second cousin; Lsc; Lsc homolog; lymphoid blast crisis like 2; lymphoid blast crisis-like 2; p115RhoGEF; p115-RhoGEF; Rho guanine nucleotide exchange factor (GEF) 1; Rho guanine nucleotide exchange factor 1; Sub1.5