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抗体

KChIP2多克隆抗体

PA5-85434

100微升

美国446.00

多克隆

domestic rabbit

未共轭

人类, 小鼠

KChIP2多克隆抗体

PA5-85434

100微升

美国446.00

多克隆

抗原亲和色谱

兔

人类, 小鼠

Western Blot: 1:500-1:3,000

人类, 小鼠

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain however, these channels prevent reverse-propagation of action potentials. Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins). KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function. There are currently three known KChIPs; KChIP1 expressed in the brain; KChIP2 expressed in the brain, heart, and lung, and has three isoforms, a, b, and c; and KChIP3, also known as calsenilin and DREAM (downstream regulatory elements (DRE)-antagonist modulator) which is expressed in the brain and testis.

Recombinant protein encompassing a sequence within the center region of human KChIP2.

液体

Western Blot: 1:500-1:3,000

A-type potassium channel modulatory protein 2; Cardiac voltage-gated potassium channel modulatory subunit; DKFZp566L1246; KCHIP2; KChlP2; Kcnip2; Kv channel interacting protein 2; Kv channel-interacting protein; Kv channel-interacting protein 2; MGC17241; potassium channel auxiliary subunit KCHIP2; potassium channel-interacting protein 2; potassium voltage-gated channel interacting protein 2; si:ch73-173h19.2