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抗体

TXK多克隆抗体

PA5-98222

100微克

美国436.00

多克隆

domestic rabbit

未共轭

人类, 大鼠

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片

TXK多克隆抗体

PA5-98222

100微克

美国436.00

多克隆

蛋白质G

兔

人类, 大鼠

ELISA: Assay-Dependent, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:500-1:5,000

人类, 大鼠

IgG

-20°C or -80°C if preferred

TXK, along with the close relatives BMS, ITK, and BTK, signal downstream of antigen receptors and other types of receptors. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton's disease. The Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated.

重组人类酪氨酸蛋白激酶TXK蛋白(32-83AA)

液体

ELISA: Assay-Dependent, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:500-1:5,000

A130089B16Rik; BTKL; Protein-tyrosine kinase 4; PSCTK5; PTK4; PTK4 protein tyrosine kinase 4; PTK-RL-18; resting lymphocyte kinase; Rlk; TKL; TXK; TXK tyrosine kinase; tyrosine kinase; tyrosine-protein kinase TXK