产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
蛋白
产品名称 :
人类DOK1合成肽
目录 :
PEP-0257
规格 :
50微克
价格 :
美国152
更多信息或购买 :
产品信息
产品类型 :
多肽
产品名称 :
人类DOK1合成肽
目录# :
PEP-0257
规格 :
50微克
定价 :
美国152
克隆性 :
Synthetic
纯度 :
纯化
反应物种 :
人类
应用 :
Blocking assay: Assay-dependent, Control: Assay-dependent
物种 :
人类
储存 :
-20°C
描述 :
DOK1 (P62dok, Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration. DOK1 is a major substrate for many tyrosine kinases including c-kit, v-abl, vFPS, EGF, and PDGF. Upon phosphorylation by kinases, DOK1 forms a complex with ras GTPase-activating protein. Phosphorylation on tyrosine residues by the insulin receptor kinase results in the negative regulation of the insulin signaling pathway. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs.
格式 :
液体
应用w/稀释 :
Blocking assay: Assay-dependent, Control: Assay-dependent
别名 :
AW557123; Docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Dok; DOK 1; DOK1; Dok-1; Downstream of tyrosine kinase 1; downstream of tyrosine kinase-1; MGC117395; MGC138860; p240; p62 dok; p62(dok); p62DOK; pp62; TLP1; TP1; TROVE domain family; TROVE1; VAULT2
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公司信息
赛默飞世尔