产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD2 Monoclonal Antibody (S5.5), Qdot™ 605
目录 :
Q10172
规格 :
100微升
价格 :
美国510.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
Qdot 605
克隆名称 :
S5.5
反应物种 :
人类, 猕猴
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 6
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 猕猴; 图 4
Vargas Inchaustegui D, Demers A, Shaw J, Kang G, Ball D, Tuero I, et al. Vaccine Induction of Lymph Node-Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques. J Immunol. 2016;196:1700-10 pubmed 出版商
Sangare K, Helmold Hait S, Moore M, Hogge C, Hoang T, Rahman M, et al. E4orf1 Suppresses E1B-Deleted Adenovirus Vaccine-Induced Immune Responses. Vaccines (Basel). 2022;10: pubmed 出版商
Musich T, Thovarai V, Venzon D, Mohanram V, Tuero I, Miller Novak L, et al. A Prime/Boost Vaccine Regimen Alters the Rectal Microbiome and Impacts Immune Responses and Viremia Control Post-Simian Immunodeficiency Virus Infection in Male and Female Rhesus Macaques. J Virol. 2020;94: pubmed 出版商
Lunemann S, Martrus G, Goebels H, Kautz T, Langeneckert A, Salzberger W, et al. Hobit expression by a subset of human liver-resident CD56bright Natural Killer cells. Sci Rep. 2017;7:6676 pubmed 出版商
Mohanram V, Demberg T, Musich T, Tuero I, Vargas Inchaustegui D, Miller Novak L, et al. B Cell Responses Associated with Vaccine-Induced Delayed SIVmac251 Acquisition in Female Rhesus Macaques. J Immunol. 2016;197:2316-24 pubmed 出版商
Demberg T, Mohanram V, Musich T, Brocca Cofano E, McKinnon K, Venzon D, et al. Loss of marginal zone B-cells in SHIVSF162P4 challenged rhesus macaques despite control of viremia to low or undetectable levels in chronic infection. Virology. 2015;484:323-33 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD2 Monoclonal Antibody (S5.5), Qdot™ 605
目录# :
Q10172
规格 :
100微升
价格 :
美国510.00
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: Assay-dependent
物种 :
人类
克隆 :
S5.5
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells. CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it. The interaction between CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection. Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.
免疫原 :
CD2抗原
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent
别名 :
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国