产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
蛋白
产品名称 :
人类IL-10重组蛋白
目录 :
RIL1025
规格 :
25微克
价格 :
美国828.00
更多信息或购买 :
产品信息
产品类型 :
蛋白
产品名称 :
人类IL-10重组蛋白
目录# :
RIL1025
规格 :
25微克
价格 :
美国828.00
克隆性 :
重组
纯度 :
纯化
反应物种 :
人类
应用 :
Control: Assay-dependent, ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
物种 :
人类
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
格式 :
冻干
应用w/稀释 :
Control: Assay-dependent, ELISA: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: Assay-dependent
别名 :
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
更多信息或购买 :
公司信息
赛默飞世尔