产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TRAC单克隆抗体(3A8)
目录 :
TCR1145
规格 :
200微克
价格 :
美国432
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3A8
反应物种 :
fission yeast, 人类
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 10
| 出版应用/物种/样本/稀释 | 参考文献 |
|---|---|
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| Buri C, Burri P, Bähler P, Straumann A, Müller Schenker B, Birrer S, et al. Cytotoxic T cells are preferentially activated in the duodenal epithelium from patients with florid coeliac disease. J Pathol. 2005;206:178-85 pubmed
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Carrasco Y, Navarro M, Toribio M. A role for the cytoplasmic tail of the pre-T cell receptor (TCR) alpha chain in promoting constitutive internalization and degradation of the pre-TCR. J Biol Chem. 2003;278:14507-13 pubmed
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Demotte N, Colau D, Ottaviani S, Godelaine D, Van Pel A, Boon T, et al. A reversible functional defect of CD8+ T lymphocytes involving loss of tetramer labeling. Eur J Immunol. 2002;32:1688-97 pubmed
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Appel H, Gauthier L, Pyrdol J, Wucherpfennig K. Kinetics of T-cell receptor binding by bivalent HLA-DR. Peptide complexes that activate antigen-specific human T-cells. J Biol Chem. 2000;275:312-21 pubmed
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Sano S, Matsui Y, Itami S, Yoshikawa K. Immunological study on CD3 defective cutaneous T cell lymphoma cells from a patient with Sézary syndrome. Clin Exp Immunol. 1998;113:190-7 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
TRAC单克隆抗体(3A8)
目录# :
TCR1145
规格 :
200微克
价格 :
美国432
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 1-2 µg/test, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: Assay-dependent
物种 :
人类
克隆 :
3A8
抗体亚型 :
IgG2a
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.
免疫原 :
Human TCR alpha chain constant region
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1-2 µg/test, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:10-1:100, Immunoprecipitation: Assay-dependent
别名 :
IMD7; T-cell receptor; T-cell receptor alpha constant; TCRA; TRA; TRAC; TRCA
更多信息或购买 :
公司信息
赛默飞世尔