产品简要
公司名称 :
徕卡显微系统(上海)贸易有限公司
其他品牌 :
Novocastra, Surgipath
产品类型 :
抗体
产品名称 :
抗肌萎缩蛋白
目录 :
NCL-DYS2
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
Dy8/6C5
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
文章摘录数: 46
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 犬; 1:20; 图 3
  • 免疫印迹; 犬; 1:40; 图 2a
  • 免疫细胞化学; 人类; 图 s20b
Amoasii L, Hildyard J, Li H, Sanchez Ortiz E, Mireault A, Caballero D, et al. Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy. Science. 2018;362:86-91 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
Fukai Y, Ohsawa Y, Ohtsubo H, Nishimatsu S, Hagiwara H, Noda M, et al. Cleavage of ?-dystroglycan occurs in sarcoglycan-deficient skeletal muscle without MMP-2 and MMP-9. Biochem Biophys Res Commun. 2017;492:199-205 pubmed 出版商
  • 免疫组化-冰冻切片; 人类
  • 免疫印迹; 人类
Papadopoulos C, Laforet P, Nectoux J, Stojkovic T, Wahbi K, Carlier R, et al. Hyperckemia and myalgia are common presentations of anoctamin-5-related myopathy in French patients. Muscle Nerve. 2017;56:1096-1100 pubmed 出版商
  • 免疫印迹; 小鼠; 1:100; 图 4c
Nelson C, Hakim C, Ousterout D, Thakore P, Moreb E, Castellanos Rivera R, et al. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science. 2016;351:403-7 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 4
Uruha A, Noguchi S, Hayashi Y, Tsuburaya R, Yonekawa T, Nonaka I, et al. Hepatitis C virus infection in inclusion body myositis: A case-control study. Neurology. 2016;86:211-7 pubmed 出版商
  • 免疫细胞化学; 犬; 图 6d
Loperfido M, Jarmin S, Dastidar S, Di Matteo M, Perini I, Moore M, et al. piggyBac transposons expressing full-length human dystrophin enable genetic correction of dystrophic mesoangioblasts. Nucleic Acids Res. 2016;44:744-60 pubmed 出版商
  • 免疫组化; 人类; 1:10; 表 1
Shah F, Berggren D, Holmlund T, Levring Jäghagen E, StÃ¥l P. Unique expression of cytoskeletal proteins in human soft palate muscles. J Anat. 2016;228:487-94 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 1
Rodríguez Muñoz R, Cárdenas Aguayo M, Alemán V, Osorio B, Chávez González O, Rendon A, et al. Novel Nuclear Protein Complexes of Dystrophin 71 Isoforms in Rat Cultured Hippocampal GABAergic and Glutamatergic Neurons. PLoS ONE. 2015;10:e0137328 pubmed 出版商
  • 免疫印迹; 人类; 1:25
Ousterout D, Kabadi A, Thakore P, Perez Pinera P, Brown M, Majoros W, et al. Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases. Mol Ther. 2015;23:523-32 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Wang Y, Mariño Enríquez A, Bennett R, Zhu M, Shen Y, Eilers G, et al. Dystrophin is a tumor suppressor in human cancers with myogenic programs. Nat Genet. 2014;46:601-6 pubmed 出版商
  • 免疫印迹; 犬; 1:100; 图 2,5
  • 免疫印迹; 小鼠; 1:100; 图 2,5
Kodippili K, Vince L, Shin J, Yue Y, Morris G, McIntosh M, et al. Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot. PLoS ONE. 2014;9:e88280 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:100; 图 1
Li D, Shin J, Duan D. iNOS ablation does not improve specific force of the extensor digitorum longus muscle in dystrophin-deficient mdx4cv mice. PLoS ONE. 2011;6:e21618 pubmed 出版商
  • 免疫印迹; 小鼠
Prins K, Lowe D, Ervasti J. Skeletal muscle-specific ablation of gamma(cyto)-actin does not exacerbate the mdx phenotype. PLoS ONE. 2008;3:e2419 pubmed 出版商
You J, Dooley M, Kim C, Kim E, Xu W, Goodman C, et al. A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodeling. Sci Signal. 2018;11: pubmed 出版商
Sánchez L, Beltran E, De Stefani A, Guo L, Shea A, Shelton G, et al. Clinical and genetic characterisation of dystrophin-deficient muscular dystrophy in a family of Miniature Poodle dogs. PLoS ONE. 2018;13:e0193372 pubmed 出版商
Carlson C, Moore S, Mathews K. Dystrophinopathy muscle biopsies in the genetic testing ERA: One center's data. Muscle Nerve. 2018;: pubmed 出版商
Huang L, Low A, Damle S, KEENAN M, Kuntz S, Murray S, et al. Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations. Genome Biol. 2018;19:4 pubmed 出版商
Randrianarison Huetz V, Papaefthymiou A, Herledan G, Noviello C, Faradova U, Collard L, et al. Srf controls satellite cell fusion through the maintenance of actin architecture. J Cell Biol. 2018;217:685-700 pubmed 出版商
Suriyonplengsaeng C, Dejthevaporn C, Khongkhatithum C, Sanpapant S, Tubthong N, Pinpradap K, et al. Immunohistochemistry of sarcolemmal membrane-associated proteins in formalin-fixed and paraffin-embedded skeletal muscle tissue: a promising tool for the diagnostic evaluation of common muscular dystrophies. Diagn Pathol. 2017;12:19 pubmed 出版商
Sakakibara I, Wurmser M, Dos Santos M, Santolini M, Ducommun S, Davaze R, et al. Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle. Skelet Muscle. 2016;6:30 pubmed 出版商
Iyombe Engembe J, Ouellet D, Barbeau X, Rousseau J, Chapdelaine P, Lagüe P, et al. Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method. Mol Ther Nucleic Acids. 2016;5:e283 pubmed 出版商
Toh Z, Thandar Aung Htut M, Pinniger G, Adams A, Krishnaswarmy S, Wong B, et al. Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies. PLoS ONE. 2016;11:e0145620 pubmed 出版商
Palazzolo G, Quattrocelli M, Toelen J, Dominici R, Anastasia L, Tettamenti G, et al. Cardiac Niche Influences the Direct Reprogramming of Canine Fibroblasts into Cardiomyocyte-Like Cells. Stem Cells Int. 2016;2016:4969430 pubmed 出版商
Murphy S, Henry M, Meleady P, Zweyer M, Mundegar R, Swandulla D, et al. Simultaneous Pathoproteomic Evaluation of the Dystrophin-Glycoprotein Complex and Secondary Changes in the mdx-4cv Mouse Model of Duchenne Muscular Dystrophy. Biology (Basel). 2015;4:397-423 pubmed 出版商
Robriquet F, Lardenois A, Babarit C, Larcher T, Dubreil L, Leroux I, et al. Differential Gene Expression Profiling of Dystrophic Dog Muscle after MuStem Cell Transplantation. PLoS ONE. 2015;10:e0123336 pubmed 出版商
Shimizu Motohashi Y, Asakura Y, Motohashi N, Belur N, Baumrucker M, Asakura A. Pregnancy-induced amelioration of muscular dystrophy phenotype in mdx mice via muscle membrane stabilization effect of glucocorticoid. PLoS ONE. 2015;10:e0120325 pubmed 出版商
Li X, Zhao L, Zhou S, Hu C, Shi Y, Shi W, et al. A comprehensive database of Duchenne and Becker muscular dystrophy patients (0-18 years old) in East China. Orphanet J Rare Dis. 2015;10:5 pubmed 出版商
Larcher T, Lafoux A, Tesson L, Remy S, Thepenier V, François V, et al. Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy. PLoS ONE. 2014;9:e110371 pubmed 出版商
Cotta A, Paim J, da Cunha Junior A, Neto R, Nunes S, Navarro M, et al. Limb girdle muscular dystrophy type 2G with myopathic-neurogenic motor unit potentials and a novel muscle image pattern. BMC Clin Pathol. 2014;14:41 pubmed 出版商
Pakula A, Schneider J, Janke J, Zacharias U, Schulz H, Hubner N, et al. Altered expression of cyclin A 1 in muscle of patients with facioscapulohumeral muscle dystrophy (FSHD-1). PLoS ONE. 2013;8:e73573 pubmed 出版商
Ousterout D, Perez Pinera P, Thakore P, Kabadi A, Brown M, Qin X, et al. Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients. Mol Ther. 2013;21:1718-26 pubmed 出版商
Heydemann A, Swaggart K, Kim G, Holley Cuthrell J, Hadhazy M, McNally E. The superhealing MRL background improves muscular dystrophy. Skelet Muscle. 2012;2:26 pubmed 出版商
Goyenvalle A, Babbs A, Wright J, Wilkins V, Powell D, Garcia L, et al. Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping. Hum Mol Genet. 2012;21:2559-71 pubmed 出版商
Arakawa R, Aoki R, Arakawa M, Saito K. Human first-trimester chorionic villi have a myogenic potential. Cell Tissue Res. 2012;348:189-97 pubmed 出版商
Fragall C, Adams A, Johnsen R, Kole R, Fletcher S, Wilton S. Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching. BMC Med Genet. 2011;12:141 pubmed 出版商
Bortolanza S, Nonis A, Sanvito F, Maciotta S, Sitia G, Wei J, et al. AAV6-mediated systemic shRNA delivery reverses disease in a mouse model of facioscapulohumeral muscular dystrophy. Mol Ther. 2011;19:2055-64 pubmed 出版商
Nishida A, Kataoka N, Takeshima Y, Yagi M, Awano H, Ota M, et al. Chemical treatment enhances skipping of a mutated exon in the dystrophin gene. Nat Commun. 2011;2:308 pubmed 出版商
de Morrée A, Lutje Hulsik D, Impagliazzo A, van Haagen H, de Galan P, van Remoortere A, et al. Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodeling. PLoS ONE. 2010;5:e11940 pubmed 出版商
Rodino Klapac L, Montgomery C, Bremer W, Shontz K, Malik V, Davis N, et al. Persistent expression of FLAG-tagged micro dystrophin in nonhuman primates following intramuscular and vascular delivery. Mol Ther. 2010;18:109-17 pubmed 出版商
Wu M, Katta A, Gadde M, Liu H, Kakarla S, Fannin J, et al. Aging-associated dysfunction of Akt/protein kinase B: S-nitrosylation and acetaminophen intervention. PLoS ONE. 2009;4:e6430 pubmed 出版商
Friedrich O, von Wegner F, Chamberlain J, Fink R, Rohrbach P. L-type Ca2+ channel function is linked to dystrophin expression in mammalian muscle. PLoS ONE. 2008;3:e1762 pubmed 出版商
Mattei E, Corbi N, Di Certo M, Strimpakos G, Severini C, Onori A, et al. Utrophin up-regulation by an artificial transcription factor in transgenic mice. PLoS ONE. 2007;2:e774 pubmed
Aartsma Rus A, Janson A, van Ommen G, van Deutekom J. Antisense-induced exon skipping for duplications in Duchenne muscular dystrophy. BMC Med Genet. 2007;8:43 pubmed
Rodriguez A, Pisani D, Dechesne C, Turc Carel C, Kurzenne J, Wdziekonski B, et al. Transplantation of a multipotent cell population from human adipose tissue induces dystrophin expression in the immunocompetent mdx mouse. J Exp Med. 2005;201:1397-405 pubmed
Kogler G, Sensken S, Airey J, Trapp T, MUSCHEN M, Feldhahn N, et al. A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential. J Exp Med. 2004;200:123-35 pubmed
Torrente Y, Tremblay J, Pisati F, Belicchi M, Rossi B, Sironi M, et al. Intraarterial injection of muscle-derived CD34(+)Sca-1(+) stem cells restores dystrophin in mdx mice. J Cell Biol. 2001;152:335-48 pubmed
产品信息
产品代码 :
NCL-DYS2
产品名称 :
抗肌萎缩蛋白
应用 :
IHCF
公司信息
徕卡显微系统(上海)贸易有限公司
上海市黄浦区徐家汇路610号日月光中心17层
hrna@leica-microsystems.com
http://www.leica-microsystems.cn
400-820-8932 86-21-6039 6000
Leica Microsystems是德国著名的光学制造企业,是全球知名的显微系统供应商。