Kon N, Wang D, Gu W. Loss of SET reveals both the p53-dependent and the p53-independent functions in vivo. Cell Death Dis. 2019;10:237 pubmed 出版商

Mello S, Valente L, Raj N, Seoane J, Flowers B, McClendon J, et al. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Cancer Cell. 2017;32:460-473.e6 pubmed 出版商

Evsyukov V, Domanskyi A, Bierhoff H, Gispert S, Mustafa R, Schlaudraff F, et al. Genetic mutations linked to Parkinson's disease differentially control nucleolar activity in pre-symptomatic mouse models. Dis Model Mech. 2017;10:633-643 pubmed 出版商

Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard Levin Z, et al. Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes Dev. 2017;31:463-480 pubmed 出版商

Barilari M, Bonfils G, Treins C, Koka V, De Villeneuve D, Fabrega S, et al. ZRF1 is a novel S6 kinase substrate that drives the senescence programme. EMBO J. 2017;36:736-750 pubmed 出版商

Ritschka B, Storer M, Mas A, Heinzmann F, Ortells M, Morton J, et al. The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration. Genes Dev. 2017;31:172-183 pubmed 出版商

Guan X, Lapak K, Hennessey R, Yu C, Shakya R, Zhang J, et al. Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth. Mol Cancer Res. 2017;15:237-249 pubmed 出版商

Schafer C, Göder A, Beyer M, Kiweler N, Mahendrarajah N, Rauch A, et al. Class I histone deacetylases regulate p53/NF-?B crosstalk in cancer cells. Cell Signal. 2017;29:218-225 pubmed 出版商

Chiche A, Moumen M, Romagnoli M, Petit V, Lasla H, Jézéquel P, et al. p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors. Oncogene. 2017;36:2355-2365 pubmed 出版商

King B, Boccalatte F, Moran Crusio K, Wolf E, Wang J, Kayembe C, et al. The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells. Nat Immunol. 2016;17:1312-1321 pubmed 出版商

Muzumdar M, Dorans K, Chung K, Robbins R, Tammela T, Gocheva V, et al. Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers. Nat Commun. 2016;7:12685 pubmed 出版商

Vermeij W, Dollé M, Reiling E, Jaarsma D, Payan Gomez C, Bombardieri C, et al. Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice. Nature. 2016;537:427-431 pubmed 出版商

Walton J, Blagih J, Ennis D, Leung E, Dowson S, Farquharson M, et al. CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma. Cancer Res. 2016;76:6118-6129 pubmed

Lesina M, Wörmann S, Morton J, Diakopoulos K, Korneeva O, Wimmer M, et al. RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis. J Clin Invest. 2016;126:2919-32 pubmed 出版商

Itahana Y, Zhang J, Göke J, Vardy L, Han R, Iwamoto K, et al. Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells. Sci Rep. 2016;6:28112 pubmed 出版商

Seidel P, Remus M, Delacher M, Grigaravicius P, Reuss D, Frappart L, et al. Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis. Oncotarget. 2016;7:23006-18 pubmed 出版商

Jaber S, Toufektchan E, Lejour V, Bardot B, Toledo F. p53 downregulates the Fanconi anaemia DNA repair pathway. Nat Commun. 2016;7:11091 pubmed 出版商

Li T, Liu X, Jiang L, MANFREDI J, Zha S, Gu W. Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging. Oncotarget. 2016;7:11838-49 pubmed 出版商

Barroso González J, Auclair S, Luan S, Thomas L, Atkins K, Aslan J, et al. PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage. Cell Death Differ. 2016;23:1448-57 pubmed 出版商

Krais A, Speksnijder E, Melis J, Indra R, Moserova M, Godschalk R, et al. The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. Arch Toxicol. 2016;90:839-51 pubmed 出版商

Aden K, Bartsch K, Dahl J, Reijns M, Esser D, Sheibani Tezerji R, et al. Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice. Gastroenterology. 2019;156:145-159.e19 pubmed 出版商

Mahdi A, Huo Y, Tan Y, Simhadri S, Vincelli G, Gao J, et al. Evidence of Intertissue Differences in the DNA Damage Response and the Pro-oncogenic Role of NF-?B in Mice with Disengaged BRCA1-PALB2 Interaction. Cancer Res. 2018;78:3969-3981 pubmed 出版商

Brandt L, Albers J, Hejhal T, Pfundstein S, Gonçalves A, Catalano A, et al. Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma. Oncotarget. 2018;9:19753-19766 pubmed 出版商

Canli O, Nicolas A, Gupta J, Finkelmeier F, Goncharova O, Pesic M, et al. Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis. Cancer Cell. 2017;32:869-883.e5 pubmed 出版商

Gonçalves A, Adlesic M, Brandt S, Hejhal T, Harlander S, Sommer L, et al. Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells. Nat Commun. 2017;8:1466 pubmed 出版商

Van T, Polykratis A, Straub B, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017;127:2662-2677 pubmed 出版商

Laos M, Sulg M, Herranen A, Anttonen T, Pirvola U. Indispensable role of Mdm2/p53 interaction during the embryonic and postnatal inner ear development. Sci Rep. 2017;7:42216 pubmed 出版商

Tonelli C, Morelli M, Sabò A, Verrecchia A, Rotta L, Capra T, et al. Genome-wide analysis of p53-regulated transcription in Myc-driven lymphomas. Oncogene. 2017;36:2921-2929 pubmed 出版商

Kucab J, Hollstein M, Arlt V, Phillips D. Nutlin-3a selects for cells harbouring TP53 mutations. Int J Cancer. 2017;140:877-887 pubmed 出版商

Delbridge A, Pang S, Vandenberg C, Grabow S, Aubrey B, Tai L, et al. RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in p53-deficient mice. J Exp Med. 2016;213:2039-48 pubmed 出版商

Page A, Navarro M, Suárez Cabrera C, Alameda J, Casanova M, Paramio J, et al. Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53. Oncotarget. 2016;7:20902-18 pubmed 出版商

Kucab J, Zwart E, van Steeg H, Luijten M, Schmeiser H, Phillips D, et al. TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts. DNA Repair (Amst). 2016;39:21-33 pubmed 出版商

Piazzolla D, Palla A, Pantoja C, Canamero M, de Castro I, Ortega S, et al. Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia. Nat Commun. 2014;5:4226 pubmed 出版商