产品简要
公司名称 :
徕卡显微系统(上海)贸易有限公司
其他品牌 :
Novocastra, Surgipath
产品类型 :
抗体
产品名称 :
p53
目录 :
P53-CM5P
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 免疫组化-石蜡切片
文章摘录数: 29
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:250; 图 6a
Maurizy C, Abeza C, Lemmers B, Gabola M, Longobardi C, Pinet V, et al. The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium. Nat Commun. 2021;12:4810 pubmed 出版商
  • 免疫组化; 小鼠; 图 2g
Flowers B, Xu H, Mulligan A, Hanson K, Seoane J, Vogel H, et al. Cell of Origin Influences Pancreatic Cancer Subtype. Cancer Discov. 2021;11:660-677 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 4c
  • 免疫沉淀; 人类; 图 1h
  • 免疫印迹; 人类; 图 1h
  • 免疫沉淀; 小鼠; 图 4e
  • 免疫印迹; 小鼠; 图 4e
Wang D, Kon N, Lasso G, Jiang L, Leng W, Zhu W, et al. Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode. Nature. 2016;538:118-122 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2
Guinot A, Oeztuerk Winder F, Ventura J. miR-17-92/p38? Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression. Cancer Res. 2016;76:4012-22 pubmed 出版商
Van t Sant L, White J, Hoeijmakers J, Vermeij W, Jaarsma D. In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration. Acta Neuropathol Commun. 2021;9:94 pubmed 出版商
Ma S, McGuire M, Mangala L, Lee S, Stur E, Hu W, et al. Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype. Cell Rep. 2021;34:108726 pubmed 出版商
Peng T, Zhai Y, Atlasi Y, ter Huurne M, Marks H, Stunnenberg H, et al. STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells. Genome Biol. 2020;21:243 pubmed 出版商
Martire S, Nguyen J, Sundaresan A, Banaszynski L. Differential contribution of p300 and CBP to regulatory element acetylation in mESCs. BMC Mol Cell Biol. 2020;21:55 pubmed 出版商
Li Q, Mao F, Zhou B, Huang Y, Zou Z, Dendekker A, et al. p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells. Cell Rep. 2020;30:465-480.e6 pubmed 出版商
Chylinski K, Hubmann M, Hanna R, Yanchus C, Michlits G, Uijttewaal E, et al. CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci. Nat Commun. 2019;10:5454 pubmed 出版商
Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed 出版商
Ou H, Kim C, Uszkoreit S, Wickström S, Schumacher B. Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells. Dev Cell. 2019;50:167-183.e8 pubmed 出版商
Teo Y, Rattanavirotkul N, Olova N, Salzano A, Quintanilla A, Tarrats N, et al. Notch Signaling Mediates Secondary Senescence. Cell Rep. 2019;27:997-1007.e5 pubmed 出版商
Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D Elia E, et al. p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value. Cell Rep. 2019;26:624-638.e8 pubmed 出版商
Aden K, Bartsch K, Dahl J, Reijns M, Esser D, Sheibani Tezerji R, et al. Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice. Gastroenterology. 2019;156:145-159.e19 pubmed 出版商
Furuuchi R, Shimizu I, Yoshida Y, Hayashi Y, Ikegami R, Suda M, et al. Boysenberry polyphenol inhibits endothelial dysfunction and improves vascular health. PLoS ONE. 2018;13:e0202051 pubmed 出版商
Mahdi A, Huo Y, Tan Y, Simhadri S, Vincelli G, Gao J, et al. Evidence of Intertissue Differences in the DNA Damage Response and the Pro-oncogenic Role of NF-?B in Mice with Disengaged BRCA1-PALB2 Interaction. Cancer Res. 2018;78:3969-3981 pubmed 出版商
Brandt L, Albers J, Hejhal T, Pfundstein S, Gonçalves A, Catalano A, et al. Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma. Oncotarget. 2018;9:19753-19766 pubmed 出版商
Canli O, Nicolas A, Gupta J, Finkelmeier F, Goncharova O, Pesic M, et al. Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis. Cancer Cell. 2017;32:869-883.e5 pubmed 出版商
Gonçalves A, Adlesic M, Brandt S, Hejhal T, Harlander S, Sommer L, et al. Evidence of renal angiomyolipoma neoplastic stem cells arising from renal epithelial cells. Nat Commun. 2017;8:1466 pubmed 出版商
Mello S, Valente L, Raj N, Seoane J, Flowers B, McClendon J, et al. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Cancer Cell. 2017;32:460-473.e6 pubmed 出版商
Van T, Polykratis A, Straub B, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017;127:2662-2677 pubmed 出版商
Tonelli C, Morelli M, Sabò A, Verrecchia A, Rotta L, Capra T, et al. Genome-wide analysis of p53-regulated transcription in Myc-driven lymphomas. Oncogene. 2017;36:2921-2929 pubmed 出版商
Delbridge A, Pang S, Vandenberg C, Grabow S, Aubrey B, Tai L, et al. RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in p53-deficient mice. J Exp Med. 2016;213:2039-48 pubmed 出版商
Vermeij W, Dollé M, Reiling E, Jaarsma D, Payan Gomez C, Bombardieri C, et al. Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice. Nature. 2016;537:427-431 pubmed 出版商
Seidel P, Remus M, Delacher M, Grigaravicius P, Reuss D, Frappart L, et al. Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis. Oncotarget. 2016;7:23006-18 pubmed 出版商
Page A, Navarro M, Suárez Cabrera C, Alameda J, Casanova M, Paramio J, et al. Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53. Oncotarget. 2016;7:20902-18 pubmed 出版商
Krais A, Speksnijder E, Melis J, Indra R, Moserova M, Godschalk R, et al. The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. Arch Toxicol. 2016;90:839-51 pubmed 出版商
Piazzolla D, Palla A, Pantoja C, Canamero M, de Castro I, Ortega S, et al. Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia. Nat Commun. 2014;5:4226 pubmed 出版商
公司信息
徕卡显微系统(上海)贸易有限公司
上海市黄浦区徐家汇路610号日月光中心17层
hrna@leica-microsystems.com
http://www.leica-microsystems.cn
400-820-8932 86-21-6039 6000
Leica Microsystems是德国著名的光学制造企业,是全球知名的显微系统供应商。