产品简要
公司名称 :
LifeSpan Biosciences
产品类型 :
抗体
产品名称 :
PathPlus™ ITGAM / CD11b Antibody (clone M1/70.15) LS-B3760
目录 :
LS-B3760
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
M1/70.15
反应物种 :
人类, 小鼠
应用 :
免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
LifeSpan Biosciences 产品网页
图像
图像 1 :
LifeSpan Biosciences LS-B3760 图像 1
Anti-CD11b antibody IHC of mouse spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
产品信息
抗体编号 :
111779
抗体名称 :
LS-B3760
目标物种 :
小鼠
宿主物种 :
大鼠
产品名称 :
PathPlus™ ITGAM / CD11b Antibody (clone M1/70.15) LS-B3760
特异性 :
Recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor. This product is routinely tested in flow cytometry on mouse peritoneal macrophages.
克隆描述 :
单克隆
克隆名称 :
M1/70.15
抗体修饰 :
未共轭
样品状态 :
PBS, 0.09% 叠氮化钠
免疫原类型 :
细胞
免疫原描述 :
T cell enriched splenocytes from B10 mice
纯化描述 :
离子交换层析
推荐的储存条件 :
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
抗体亚型 :
IgG2b
基因 :
ITGAM/CD11b
标准基因符号 :
ITGAM
家族 :
整合素
反应物种 :
兔, 小鼠, 人类
用途 :
Flo (1:50), IF, IHC, IHC-Fr, IHC-P (10 µg/ml), IP
ShortWebDescription :
CD11b antibody LS-B3760 is an unconjugated rat monoclonal antibody to CD11b (ITGAM) from mouse. It is reactive with human, mouse and rabbit. Validated for Flow, IF, IHC and IP.
使用文本 :
Immunohistochemistry: LS-B3760 was validated for use in immunohistochemistry on a panel of formalin-fixed, paraffin-embedded (FFPE) mouse tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3760 was determined to be 10 ug/ml.
同义词 :
ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
SalesRegion :
Worldwide
更多信息或购买 :
LifeSpan Biosciences 产品网页
公司信息
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
公司总部: 美国
LifeSpan成立于1995年，已经成为分子病理学领域的领导品牌，专注于人和其他物种的正常和疾病组织中蛋白的定位情况。我们提供超过74000种抗体，定制的免疫组化研究服务，超过500种蛋白研究用人免疫组化材料，及组化和病理学服务；提供2,000,000样本，包括冰冻及石蜡切片的正常和疾病组织，进行对外研究服务。对外服务项目范围广泛，由LifeSpan的病理学家提供包括课题设计、抗体搜寻及表征、组织搜集和验证、免疫标记、问题处理及结果处理等诸多环节。