抗体

GFAP抗体(克隆G-A)LS-C347458

LS-C347458

单克隆

小鼠

未共轭

G-A-5

免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片

LS-C347458

人类

小鼠

GFAP抗体(克隆G-A)LS-C347458

Recognizes GFAP in human, mouse, rat, porcine and chicken. The antibody reacts with the carboxyterminal cys II fragment of GFAP as determined by western blotting and does not cross react with vimentin.

单克隆

G-A-5

未共轭

PBS, 0.09% 叠氮化钠

细胞

G-A-5 is a mouse monoclonal IgG1 antibody derived by fusion of PA1 mouse myeloma cells with spleen cells from BALB/c mice immunized with purified GFAP from porcine spinal cord.

纯化

Store at 4°C, or in small aliquots at -20°C.

IgG1

GFAP

GFAP

鸡, 大鼠, 猪, 小鼠, 人类

ICC, IHC, IHC-Fr, IHC-P, WB

GFAP antibody LS-C347458 is an unconjugated mouse monoclonal antibody to GFAP from human. It is reactive with human, mouse, rat and other species. Validated for ICC, IHC and WB.

Glial fibrillary acidic protein(GFAP) is a class III intermediate filament protein, a cytoskeletal protein that is located within the cytoplasm of astrocyctes and other glial cells e. g. Schwann cells and ependymal cells. In the central nervous system, GFAP is the major intermediate filament protein of mature astrocytes. GFAP plays an important role in maintaining the structure and stability of astrocytes during development and has also been shown to be involved in cellular communication, motility and mitosis. Mutations in GFAP give rise to Alexander disease, a rare and fatal disease of the central nervous system. Antibodies recognizing GFAP are commonly used to identify cells of astrocytic origin under normal and pathological conditions.

GFAP

Worldwide