抗体

CCL5/RANTES抗体LS-C42727

LS-C42727

多克隆

domestic rabbit

未共轭

免疫印迹, 酶联免疫吸附测定, 免疫组化-石蜡切片

LS-C42727

人类

兔

CCL5/RANTES抗体LS-C42727

Recognizes human RANTES (regulated upon activation, normal T cell expressed and secreted), otherwise known as CCL5, a 68 amino acid CC- chemokine involved in T cell activation and cell recruitment, expressed by cytotoxic (CD8+) T cells (CTLs), macrophages, keratinocytes and endothelial cells. RANTES acts as a chemoattractant for monocytes, CD4+/CD45RO+ memory T cells, basophils and eosinophils, thorough binding to chemokine (C-C motif) receptor 1 (CCR1), CCR3 and CCR5. Both CCR3 and CCR5 are known co-receptors for the entry of HIV viruses into target cells and the binding of RANTES to CCR3 on CTLs has been shown to enhance HIV-1-specific cytotoxicity, whilst binding to CCR5 inhibits membrane fusion and hence HIV entry.

多克隆

未共轭

PBS

重组蛋白

重组人类RANTES

纯化

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

Distilled Water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add azide.

IgG

CCL5/RANTES

CCL5

Intercrine

人类

酶联免疫吸附测定(0.5-2微克/毫升), 免疫组化-P, 免疫印迹(0.1-0.2微克/毫升)

RANTES antibody LS-C42727 is an unconjugated rabbit polyclonal antibody to human RANTES (CCL5). Validated for ELISA, IHC and WB.

ELISA: May be used in an indirect ELISA or as a capture reagent in a sandwich ELISA. Western Blot: May be used in either reducing or non-reducing conditions.

CCL5, Chemokine (C-C motif) ligand 5, D17S136E, EoCP, T-cell specific protein p288, SCYA5, SISd, T cell-specific protein P228, Beta-chemokine RANTES, C-C motif chemokine 5, RANTES, SIS-delta, Small-inducible cytokine A5, T-cell-specific protein RANTES, TCP228

Worldwide