抗体

CD86抗体(克隆BU63)LS-C43296

LS-C43296

单克隆

小鼠

未共轭

BU63

免疫组化, 免疫沉淀, 流式细胞仪, 免疫组化-冰冻切片

LS-C43296

人类

小鼠

CD86抗体(克隆BU63)LS-C43296

Recognizes human CD86 also known as B7-2, a type I transmembrane protein expressed by monocytes and activated B cells. CD86 acts as a co-stimulatory molecule along with CD80 and is a ligand for CD28 and CTLA-4. CD86 is a member of the Immunoglobulin superfamily and carries an extracellular domain bearing both an domain which contains the CTLA-4 binding site and an adjacent C2-like domain. CD86 plays an important role in co-stimulation of T cell proliferation, IL-2 production and in the primary immune response. Domain depletion epitope mapping studies indicate that the binding site of Mouse anti Human CD86, is located within the Ig-v-like domain of human CD86. Studies suggest that CD86 along with CD80 may be exploited as receptors for adenovirus entry into cells.

单克隆

BU63

未共轭

PBS, 0.09% 叠氮化钠

细胞

Human peripheral blood lymphocytes.

蛋白质A纯化

Short term: store at 4°C. Long term: store at -20°C.

IgG1

CD86

CD86

人类

Flo (1:20 - 1:100), IHC, IHC-Fr (1:20 - 1:100), IP

CD86 antibody LS-C43296 is an unconjugated mouse monoclonal antibody to human CD86. Validated for Flow, IHC and IP.

Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2

Worldwide