抗体

TP53/p53抗体(aa20-25, 克隆DO-1, 生物素)LS-C43827

LS-C43827

单克隆

小鼠

生物素

DO-1

LS-C43827

人类

小鼠

TP53/p53抗体(aa20-25, 克隆DO-1, 生物素)LS-C43827

Recognizes the human p53 tumor suppressor protein, also known as cellular tumor antigen p53 or NY-CO-13. Clone DO-1 binds to both wild type and mutant forms of the p53 protein found in various malignancies. p53 is important in multicellular organisms, where it regulates cell cycle progression to allow DNA repair or apoptosis in the case of irreparably damaged cells and thus functions as a tumor suppressor that is involved in preventing cancer. Mutations in the p53 gene are found in about half the cases of human cancerrecognizes an epitope at the N-terminal end of p53 between amino acids 20-25, common to isoforms 1-3 of p53.

单克隆

DO-1

生物素

aa20-25

PBS, 0.09% 叠氮化钠, 1% BSA

重组蛋白

重组人类p53(氨基酸20-25)

蛋白质G纯化

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

IgG2a

TP53/p53

TP53

P53

人类

小鼠, 大鼠

免疫组化-P

P53 antibody LS-C43827 is a biotin-conjugated mouse monoclonal antibody to human p53 (TP53) (aa20-25). Validated for IHC.

Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 whole blood in 100 ul. Membrane permeabilization is required for this application. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1

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