抗体

IRF5抗体(aa176-240, 克隆10T1)LS-C45031

LS-C45031

单克隆

小鼠

未共轭

10T1

免疫印迹, 酶联免疫吸附测定, 免疫沉淀, 免疫组化-石蜡切片

LS-C45031

人类

小鼠

IRF5抗体(aa176-240, 克隆10T1)LS-C45031

Recognizes human interferon regulatory factor 5 (IRF5), a 58kD member of the IRF family which acts as a key regulator of interferon gene transcription, and is expressed in B cells and dendritic cells, and is inducible by type I interferon (IFN) in most lymphoid cells. The role of IRF3 and IRF7 as transcriptional mediators of virus- and IFN-induced signaling pathways is well documented. Studies have shown that IRF5 can also regulate IFN gene transcription, but appears to be more restricted in its cellular expression and range of viral stimuli, and has the ability to induce a wide range of chemokines involved in T-lymphocyte recruitment, including RANTES, MCP-1 and IP-10.

单克隆

10T1

未共轭

aa176-240

PBS, 0.1% 叠氮化钠

重组蛋白

重组人类IRF5(176-240aa)纯化来自大肠杆菌

蛋白质G纯化

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

IgG1

IRF5

IRF5

人类

酶联免疫吸附测定, 免疫组化-P, 免疫沉淀, 免疫印迹(1:1000 - 1:2000)

IRF5 antibody LS-C45031 is an unconjugated mouse monoclonal antibody to human IRF5 (aa176-240). Validated for ELISA, IHC, IP and WB.

Western Blot: LS-C45031 detects a band of approximately 58kD in THP-1 cell lysates.

IRF5, 干扰素调节因子5, IRF-5, SLEB10, IBD14

Worldwide