抗体

FZD9 / Frizzled 9 Antibody (FITC) LS-C498896

LS-C498896

多克隆

domestic rabbit

异硫氰酸荧光素

LS-C498896

人类

兔

FZD9 / Frizzled 9 Antibody (FITC) LS-C498896

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

多克隆

异硫氰酸荧光素

PBS, pH值7.4, 0.03% ProClin防腐剂300, 50% 甘油

重组蛋白

Recombinant Human Frizzled-9 protein (23-229AA)

蛋白质G纯化

Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.

IgG

FZD9 / Frizzled 9

FZD9

GPCR

Frizzled

人类

酶联免疫吸附测定

Frizzled 9 antibody LS-C498896 is an FITC-conjugated rabbit polyclonal antibody to human Frizzled 9 (FZD9). Validated for ELISA.

FZD9, CD349, Frizzled homolog 9, Fz-9, Frizzled family receptor 9, Frizzled-9, Frizzled 9, Fz9, HFz9, CD349 antigen, Frizzled homolog fzd3, FzE6

Worldwide