抗体

PDCD1/CD279/PD-1抗体(克隆RMP1-30)LS-C57984

LS-C57984

单克隆

大鼠

未共轭

RMP1-30

人类, 小鼠

LS-C57984

小鼠

大鼠

PDCD1/CD279/PD-1抗体(克隆RMP1-30)LS-C57984

Recognizes mouse CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279. Antibodies produced by clone RMP1-30 do not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.

单克隆

RMP1-30

未共轭

PBS, 0.09% 叠氮化钠

细胞

PD-1转移BHK细胞

亲和纯化

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

IgG2b

PDCD1/CD279/PD-1

PDCD1

凋亡

小鼠

Flo (1:100 - 1:200)

PD-1 antibody LS-C57984 is an unconjugated rat monoclonal antibody to mouse PD-1 (PDCD1 / CD279). Validated for Flow.

Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

PDCD1, CD279, HPD-1, HPD-l, PD1, Protein PD-1, SLEB2, PD-1, CD279 antigen, Programmed cell death 1

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