产品简要
公司名称 :
LifeSpan Biosciences
产品类型 :
蛋白
产品名称 :
小鼠SDF1/CXCL12蛋白(重组)(Lys22-Lys89)- LS-G27012
目录 :
LS-G27012
更多信息或购买 :
产品信息
ProteinId :
27012
目录号 :
LS-G27012
产品名称 :
小鼠SDF1/CXCL12蛋白(重组)(Lys22-Lys89)- LS-G27012
描述 :
SDF-1 a and SDF-1 Beta, members of the chemokine a subfamily that lack the ELR domain, were initially identified using the signal sequence trap cloning strategy from a mouse bone-marrow stromal cell line. SDF-1 a and SDF-1 Beta cDNAs encode precursor proteins of 89 and 93 amino acid residues, respectively. Both SDF-1 a and SDF-1 Beta are encoded by a single gene and arise by alternative splicing. The two proteins are identical except for the four amino acid residues that are present in the carboxy-terminus of SDF-1 Beta and absent from SDF-1 a. SDF-1/PBSF is highly conserved between species, with only one amino acid substitution between the mature human and mouse proteins. SDF-1/PBSF acts via the chemokine receptor CXCR4 and has been shown to be a chemoattractant for T-lymphocytes, monocytes, pro- and pre-B cells, but not neutrophils. Mice lacking SDF-1 or CXCR4 have been found to have impaired B-lymphopoiesis, myelopoiesis, vascular development, cardiogenesis and abnormal neuronal cell migration and patterning in the central nervous system. Recombinant Mouse SDF-1 a/CXCL12 produced in CHO cells is a polypeptide chain containing 68 amino acids. A fully biologically active molecule, rm SDF-1 Beta/CXCL12 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
样品状态 :
冻干来自PBS
ProteinType :
重组
ProteinSpecies :
小鼠
ProteinSourceSpecies :
仓鼠中国人
RecommendedStorage :
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 3 months.
ReconstitutionInstructions :
Reconstitute in ddH2O or PBS at 100 µg/ml.
纯化 :
Greater than 95% by SDS-PAGE
PredictedMolecularWeight :
8 kDa (SDS-PAGE)
基因 :
SDF1/CXCL12
标准基因符号 :
CXCL12
亚家族 :
Intercrine alpha
家族 :
Intercrine
同义词 :
CXCL12, C-X-C motif chemokine 12, HIRH, IRH, SDF-1, SDF-1b, SDF1A, SDF1B, TPAR1, TLSF-a, TLSF-b, SDF-1a, SDF1, Sdf1alpha, Stromal cell-derived factor 1, TLSF, HSDF-1, PBSF, SCYB12
SalesRegion :
Worldwide
更多信息或购买 :
公司信息
LifeSpan Biosciences
2401 Fourth Avenue, Suite 900
Seattle, WA 98121
antibodies@lsbio.com
https://www.lsbio.com
1-206-464-1554
公司总部: 美国
LifeSpan成立于1995年,已经成为分子病理学领域的领导品牌,专注于人和其他物种的正常和疾病组织中蛋白的定位情况。我们提供超过74000种抗体,定制的免疫组化研究服务,超过500种蛋白研究用人免疫组化材料,及组化和病理学服务;提供2,000,000样本,包括冰冻及石蜡切片的正常和疾病组织,进行对外研究服务。对外服务项目范围广泛,由LifeSpan的病理学家提供包括课题设计、抗体搜寻及表征、组织搜集和验证、免疫标记、问题处理及结果处理等诸多环节。